Healthy Children for a Healthy Future (HC4HF):A Collaborative Health Disp. Res.*

描述（由申请人提供）：在各种暴露、条件、疾病和治疗中，儿童的健康存在着充分记录的、普遍的和不可接受的种族和民族差异。这种差异不仅直接给儿童自身、家庭和社区造成负担，而且还会对几代人产生长期影响。华盛顿特区-巴尔的摩地区的特点是严重的收入不平等、居住隔离和儿童健康方面的显著差异。这项更新申请建立了健康儿童的健康未来：协作健康差异卓越研究中心（HC4HF），并建立在霍华德大学（HU）、国家儿童医学中心（CNMC）和约翰霍普金斯大学儿科（JH）长期合作承诺的基础上，在dc -巴尔的摩儿童健康差异研究中心下进行儿童健康差异研究和培训。我们的工作结合了儿童健康差异的概念模型和寿命视角，并特别致力于开发干预措施以克服儿童健康差异。HC4HF的总体目标是为高效和有效的研究、培训和社区参与提供一个广泛合作、多学科和多机构的“家”，旨在改善少数民族儿童的健康，克服华盛顿特区-巴尔的摩地区的儿童健康差距。为了实现这一总体目标，我们提出了以下具体目标：1)：实施一项严格的干预研究计划，以优化青春期关键发育时期的健康，这一时期将早期暴露与长期成年和代际健康联系起来。这项工作将利用“移动医疗”（移动医疗）领域的新兴技术，如短信，来测试针对两种高度相关、对城市非裔美国青少年影响极大的疾病（2型糖尿病风险/肥胖和暴力暴露）的干预措施；2)培训和指导初级教师进行与少数民族健康和健康差异相关的严格研究所需的临床和转化研究技能；3)通过提供基于地理位置健康指标审查和评价的创新对话方案，加强华盛顿特区-巴尔的摩地区的双向社区参与和外联；通过将社区咨询过程纳入培训；4)：领导一个基础广泛、多学科、多机构和协作的联盟，协调和加强与华盛顿特区-巴尔的摩地区和全国少数民族儿童健康和健康差距有关的研究和培训。

DESCRIPTION (provided by applicant): There are well-documented, pervasive, and unacceptable racial and ethnic disparities in the health of children across a variety of exposures,conditions, diseases, and treatments. Such disparities not only directly burden children themselves, their families, and their communities, but also have long-term effects across multiple generations. The Washington, DC-Baltimore region is characterized by significant income inequality, residential segregation, and marked disparities in child health. This renewal application establishes the Healthy Children for a Healthy Future: a Collaborative Health Disparities Research Center of Excellence (HC4HF) and builds on the long-standing collaborative commitment of Howard University (HU), Children's National Medical Center (CNMC), and the Department of Pediatrics at Johns Hopkins (JH) to child health disparities research and training under the DC-Baltimore Research Center on Child Health Disparities. Our work incorporates a conceptual model of child health disparities and a lifespan perspective and Is specifically committed to the development of interventions to overcome child health disparities. The overall goal of HC4HF is to provide a broadly collaborative, multi-disciplinary and multi-institutional "home" for efficient and effective research, training, and community engagement designed to improve minority child health and overcome child health disparities in the Washington DC-Baltimore region. To achieve this overall goal, we address the following Specific Aims: 1): To implement a program of rigorous intervention research to optimize health during the critical developmental period of adolescence, which links early exposures to long-term adult and intergenerational health. This work will draw on emerging technologies in "mobile health" (m-health), such as text messaging, to test interventions targeting two highly relevant conditions disproportionately affecting urban African American adolescents (Type 2 diabetes risk/obesity and violence exposure); 2) To train and mentor junior faculty in the required clinical and translational research skills required to conduct rigorous research relevant to minority health and health disparities; 3) To strengthen bidirectional community engagement and outreach in the Washington, DC-Baltimore region by providing an innovative program of dialogue based on review and evaluation of geo-located health indicators; and by integrating the community advisory process into training; 4): To lead a broadly based, multi-disciplinary, multi- institutional, and collaborative consortium to coordinate and strengthen research and training relevant to child minority health and health disparities in the Washington, DC-Baltimore region and nationally.