TAS::75 0872::TAS DIVISION OF CARDIOVASCULAR SCIENCES(8470187

Peruana Cayetano Heredia大学申请了这项补充资金，以便进行一项以社区为基础的可行性试验，他们将在肯尼亚、秘鲁和尼泊尔部分地区的40户35岁至45岁的农村妇女家庭中安装带有烟囱的改良厨灶。。所有家庭将有4个月的基线观察期，在此期间他们将纵向收集结果、环境和行为数据。此后，20个家庭将被随机分配到一个商业上可以买到的改进型带烟囱的灶具，或一个当地建造的改进型带烟囱的灶具。他们将在4个月内纵向收集行为、遵从性、结果和暴露数据。暴露评估将包括颗粒物和一氧化碳。呼吸结果评估将包括肺活量、碳氧血红蛋白、呼出的一氧化氮和肺对一氧化碳的扩散能力。在4个月的月底，接受Envirofit改进型厨灶的家庭将用当地制造的改进型厨灶更换厨灶，反之亦然，所有家庭都将被跟踪观察4个月。在年底，所有参与者将被问及他们更喜欢哪种灶具，并将被要求提供影响他们最终选择的偏好、做法和使用模式的信息。这些研究将作为秘鲁和肯尼亚COES与尼泊尔营养干预项目--Sarlahi之间的合作进行。

The Universidad Peruana Cayetano Heredia applied for the supplement in order to conduct a community-based feasibility trial in which they will install improved cook stoves with a chimney in 40 rural households of women aged 35 to 45 years in some areas of Kenya, Peru and Nepal. . All households will have a baseline observational period of 4 months in which they will collect outcome, environmental, and behavioral data longitudinally. Thereafter, 20 households will be randomly assigned to receive a commercially-available, improved cook stove with a chimney or a locally-constructed improved cook stove with a chimney. They will collect behavioral, compliance, outcome and exposure data longitudinally for 4 months. Exposure assessments will include particulate matter and carbon monoxide. Respiratory outcome assessment will include spirometry, carboxyhemoglobin, exhaled nitric oxide and diffusing capacity of the lung for carbon monoxide. At the end of 4 the month period, households that received the Envirofit improved cook stoves will have their cook stoves switched with the locally-constructed improved cook stoves and vice versa, and all households will be followed for another 4 months. At the end of the year, all participants will be asked which cook stove they prefer and will be asked to provide information on preferences, practices, and use patterns that influenced their final choice. These studies will be conducted as a collaboration between the Peru and Kenya COes and the Nepal Nutrition Intervention Project-Sarlahi.