CORPUS CALLOSUM CHANGES IN MILD ALZHEIMER'S DISEASE

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 轻度阿尔茨海默病和遗忘型轻度认知障碍患者的胼胝体改变 将评估健康对照组和阿尔茨海默病和轻度认知障碍患者的胼胝体形态。将根据已定义的跟踪协议手动划定胼胝体区域。然后，将使用基于计算表面的技术来以高分辨率对膝盖骨厚度进行编码，以进行分组比较。我们希望利用神经成像实验室(LONI)开发的一种基于表面的计算方法来分析膝盖骨厚度。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Corpus Callosum Changes in Mild Alzheimer Disease and Amnesic Mild Cognitive Impairment Corpus callosum morphology will be assessed in healthy controls and patients with Alzheimer's disease and Mild Cognitive impairment. The corpus callosum region will be delineated manually following a defined tracing protocol. Computational surfaced-based techniques to encode callosal thickness at high resolution will then be applied to compare groups. We wish to analyze callosal thickness utilizing a computational surface-based approach that was developed at the Laboratory of Neuro Imaging (LONI).