Core B: DATA VISUALIZATION, SHARING AND EDUCATION

PENTACON的长期目标是成为如何将来自模型系统的数据与 并利用信息学/建模来提供逐步实现日益安全和 有效的个性化药物。因此，我们预计我们创建的数据集和方法将是 科学界普遍感兴趣的问题。更重要的是，我们有机会从事数据工作 分享、教育和传播实践，对这些活动提出了很高的期望。当然，我们的 核心传播活动将是出版与个性化使用有关的优秀科学 非甾体抗炎药，并为社区提供有效和方便使用的途径 底层数据、模型和系统。高影响力出版物在受人尊敬的期刊中的重要性 不容小觑。我们合作团队中的参与科学家有一个杰出的轨迹 在向社区传播结果、数据和方法的同时报告高影响力的科学方面的记录。这 活动将分布在整个协作过程中，并将通过指导委员会进行管理 与行政核心中所述的外部咨询委员会(EAC)合作，当 出现了复杂的作者身份问题(PENTACON网站将作为我们分发的中央门户 活动)。然而，我们认识到需要在出版之外进行教育和传播，因此建议 将利用PENTACON的活动并最大限度地发挥其对翻译的影响的四项关键活动 科学和医学。

The long-term goal of PENTACON is to be an exemplar of how to combine data from model systems and humans and to utilize informatics/modeling to provide outputs that progressively realize increasingly safe and efficacious personalized medicine. Thus, we expect that the data sets and methodologies that we create will be of general interest to the scientific community. More importantly, we have the opportunity to engage in data sharing, education, and dissemination practices that set high expectations for these activities. Of course, our core dissemination activity will be the publication of excellent science related to the individualized use of NSAID drugs, complemented by providing the community with effective and user-friendly access to the underlying data, models, and systems. The importance of high-impact publications in respected journals cannot be underestimated. The participating scientists on our collaborative team have an outstanding track record in reporting high-impact science while disseminating results, data, and methods to the community. This activity will be distributed throughout the collaboration, and will be managed through the Steering Committee in conjunction with the External Advisory Committee (EAC), as described in the Administrative Core, when complex issues of authorship arise (the PENTACON website will serve as a central portal for our distribution activity). However, we recognize a need for education and dissemination beyond publication, and so propose four critical activities that will leverage the activities of PENTACON, and maximize its impact on translational science and medicine.