Pilot Research

在这一供资期间提供了几个试点项目RFA，以具体解决中心战略规划机制和外部科学咨询委员会年度会议范围内确定的AECC目标，(I)2008年发布的第一个试点项目RFA侧重于促进临床和实验室研究人员之间的合作，目的是在临床研究的背景下促进转化性研究。要求调查员参加AECC先期务虚会上的以疾病为导向的焦点小组，(2)第二个试点项目RFA于2010年春季发布。这一倡议源于乳腺癌工作组的活动，需要在肿瘤微环境和转移计划的背景下加强乳腺癌的转化研究。RFA要求提出一系列建议，以解决导致转移的肿瘤和/或宿主因素、转移的预测标记物等问题。(Iii)第三次RFA(2011年1月)提供赠款，以支持AECC共享资源的使用，以获得支持赠款申请的初步数据。通过CCSG机制支持所有试点项目的奖励总额为350,000美元。这里介绍了CCSG支持的代表性项目。

Several pilot project RFAs were offered over this funding period to specifically address AECC goals identified within the context of the Center's strategic planning mechanism and the yearly meetings of the External Scientific Advisory Committee, (i) The first pilot project RFA issued in 2008 was focused on stimulating collaborations between clinical and laboratory investigators with the objective of promoting translational research within the context of a clinical study. A requirement was that the investigator participated in a disease-oriented focus group at the AECC Advances retreat, (ii) The second pilot project RFA was issued in Spring 2010. This initiative grew out of the Breast Cancer Working Group's activities and need to strengthen translational research in breast cancer with the context of the Tumor Microenvironment and Metastasis program. The RFA requested a range of proposals that address tumor and/or host factors contributing to metastasis, predictive markers of metastases, etc. (iii) The third RFA (January 2011) provided grants to support utilization of AECC Shared Resources in order to obtain preliminary data to support a grant application. Total awards in support of all pilot projects through the CCSG mechanism was $350,000. Representative projects supported by the CCSG are described here.