Systems Science Center for Musculoskeletal CAM Therapies

本PCCTR的总体目标是解决三个主要障碍，以提高密歇根州立大学骨科医学学院（MSUCOM）CAM研究的能力：1）缺乏标准化，客观的工具和措施，表征和优化骨科手法治疗（OMT）干预，2）缺乏可见的持续OMT研究计划和3）临床教师缺乏研究培训。 这三个研究项目的基本原理是基于OMT影响肌肉骨骼系统的感觉和/或运动功能的某些方面的总体假设。 因此，这种系统的性能改进应作为一种客观的成果衡量标准。 在项目一中，系统科学的方法将被应用于识别的缺陷，在姿势控制的个人腰痛（LBP）和评估的影响，OMT对姿势控制。 并行机器人设备，编程为模仿不稳定坐在半圆柱体上，将被用来量化平衡和姿势控制之前和之后4周的OMT在交叉实验设计。 项目二将研究OMT是否可以通过使姿势控制系统对LBP患者的此类事件做出更快、更准确的反应来减轻突然、意外躯干扰动的不良影响。 在交叉实验设计中，将在OMT 4周前后量化控制系统的速度及其准确度。 项目三将开发用于评估头颈系统运动控制的临床研究工具。 使用交叉实验设计，然后将这些工具应用于测量OMT 4周前后有和无颈部疼痛患者的头颈系统位置和力控制的变化。

The overall goal of this PCCTR is to address three major barriers to increase capacity for CAM research at Michigan State University College of Osteopathic Medicine (MSUCOM): 1) the lack of standardized, objective instruments and measures for characterizing and optimizing osteopathic manipulative therapy (OMT) interventions, 2) the lack of visible ongoing OMT research programs and 3) the lack of research training of clinical faculty. The rationale for the three research projects is based on the overall hypothesis that OMT affects some aspects of sensory and/or motor functions of the musculoskeletal system. Thus, improvement in performance of such a system should serve as an objective outcome measure. In project one, a systems science approach will be applied to identify deficits in postural control of individuals with low back pain (LBP) and assess the effects of OMT on postural control. A parallel robot device, programmed to mimic unstable sitting on a half-cylinder, will be used to quantify balance and postural control before and after 4 weeks of OMT in a cross-over experimental design. Project two will investigate whether OMT can mitigate adverse effects from a sudden, unexpected trunk perturbation by resulting in a faster and more accurate response of the postural control system to such an event in patients in LBP. The speed of the control system and its accuracy will be quantified before and after 4 weeks of OMT in a cross-over experimental design. Project three will develop clinical research tools for the assessment of motor control of the head-neck system. Using a cross-over experimental design, these tools will then be applied to measure changes in position and force control of the head-neck system in patients with and without neck pain before and after 4 weeks of OMT.