Multidisciplinary Schizophrenia Research Training

描述(由申请人提供)：这是马里兰州精神病学研究中心(MPRC)首次竞争性续签T32培训补助金的重新提交，最初资助于2003年(MH067533)。该计划的目标是培养对基础或临床研究感兴趣的医学博士、博士和药学博士，以便从事精神分裂症的翻译研究。MPRC是马里兰大学医学院精神病学系的一个部门，是一个专注于精神分裂症研究的中心，位于巴尔的摩郊外的斯普林格罗夫医院中心，这是一家住院精神健康医院。MPRC的教职员工有一个临床和神经科学研究的综合研究计划，涉及精神分裂症的神经生理学、发育起源、家族联系、症状、神经认知和治疗。这一成功的研究项目的特点是MPRC和附近的SOM园区内不同的临床前和临床研究人员之间频繁的互动和合作。根据这一T32奖学金提供的博士后培训主要集中在基础神经科学或精神分裂症的临床研究上。所有受训人员都接受了MPRC翻译视角的教育，并为精神分裂症患者提供临床和神经科学方面的指导和教学培训。重新提交的竞争性五年续期申请建议每年资助3个新的实习生职位，每个职位为期2年的研究金。虽然这是一个非常年轻的T32项目，但在招募和培训独立研究人员方面是成功的。在最初的筹资期间，有10名学员参加了培训。4名学员完成了培训计划，1名因个人原因退出，5名目前正在接受培训。在完成的4名教师中，3名拥有助理教授级别的教职(在马里兰大学巴尔的摩大学、威尔士大学班戈分校和奥斯纳布吕克大学)，1名目前受雇于MPRC担任研究助理。其中三名毕业生获得了竞争激烈的资助。一名目前的实习生将于7月份从该项目毕业，并已获得马里兰大学巴尔的摩分校的助理教授职位。此外，目前的5名受训人员中有2人获得了NARSAD青年研究员奖。 公共卫生相关性：精神分裂症等复杂问题需要一支多学科的临床研究队伍，习惯于在综合团队中工作。这项提议寻求通过招募和指导临床和临床前博士后来解决研究严重精神疾病的转化型科学家数量不断减少的问题。

DESCRIPTION (provided by applicant): This is a resubmission of the first competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in translational research in schizophrenia. The MPRC, a division of the University Of Maryland Medical School Department Of Psychiatry, is a focused center for schizophrenia research, located on the grounds of the Spring Grove Hospital Center, an inpatient mental health hospital located just outside Baltimore. The faculty of the MPRC have an integrated research program of clinical and neuroscience research into the neurophysiology, developmental origins, familial associations, symptoms, neurocognition, and treatment of schizophrenia. This successful research program is characterized by frequent interaction and collaboration among different preclinical and clinical researchers within the MPRC and nearby SOM campus. Postdoctoral training offered under this T32 fellowship has a primary focus on either basic neuroscience or clinical investigations of schizophrenia. All trainees are educated on the translational perspective of the MPRC and provided mentors and didactic training in both clinical and neuroscience in schizophrenia. This resubmission for a competitive five-year renewal application proposes to fund 3 new trainee positions in each year, with each a fellowship lasting for 2 years. Although this is a very young T32 program, it is successful in terms of recruiting and training independent researchers. During the initial funding period, 10 trainees were enrolled. Four trainees completed the training program, 1 withdrew for personal reasons and 5 are currently in training. Of the 4 that completed, 3 have faculty appointments at the Assistant Professor level (at the University of Maryland Baltimore, University of Wales, Bangor, and the University of Osnabruck) and one is currently employed at the MPRC as research associate. Three of these graduates have received competitive funding. One current trainee will graduate from this program in July and has secured an assistant professorship position at the University of Maryland Baltimore. In addition, 2 of the 5 current trainees have received competitive NARSAD Young Investigator awards. PUBLIC HEALTH RELEVANCE: Complex problems such as schizophrenia require a multidisciplinary clinical research workforce, accustomed to working in integrated teams. This proposal seeks to address the dwindling number of translational scientists studying severe mental illness by recruiting and mentoring clinical and preclinical post-docs.