Translational Proteomics: Biology, Technology and Clinical Advances

描述(由申请者提供)：我们请求为2013年3月10-13日在马里兰州巴尔的摩举行的题为“翻译蛋白质组学：生物学、技术和临床进展”的美国人类蛋白质组组织(US-HUPO)2013年年会的运作提供部分资金支持。自2005年第一次美国HUPO会议以来，对于高度跨学科的蛋白质组学科学领域，特别是针对生物和临床问题，这个会议一直是并将继续是一个重要的会议。US-HuPo是一次独特的科学家会议，因为它真实地反映了 使蛋白质组研究人员能够接近和解决复杂的生物医学问题。美国-HuPo会议致力于促进不同技术平台的临床应用和转化，包括质谱仪、蛋白质微阵列、生物传感器、临床分析和用于诊断、预后和治疗目的的生物标记物的发现和验证。美惠会议出席人数众多，一直吸引着该领域的一流演讲者。2013年年会将再次汇聚一批处于蛋白质组学前沿的杰出和多样化的科学家。研讨会的特邀演讲者将明确讨论与包括心血管疾病、癌症和传染病在内的各种疾病相关的应用。由于近年来取得的技术进步对于使科学家能够更有效地解决生物问题至关重要，蛋白质组学的技术未来也将是会议的一个标志。选定的主题将教育参与者最新、最有效的技术和方法，说明这些技术成功地应用于临床，并突出该领域未来的新方向和重大挑战。将就关键主题举行互动式小组讨论，以鼓励演讲者和与会者之间进行强有力的对话，讨论蛋白质组学未来的关键目标，概述预期的障碍，并集思广益地解决方案。今年，US-HuPo将继续在生物学、技术和临床进步方面继续举办非常成功的平行职业发展会议，为早期研究人员提供对蛋白质组学增长领域和专业发展战略的关键见解。海报会议还将提供一次更非正式的科学思想和进步交流。将有充足的时间用于社交场所，让与会者相互见面，建立新的联系和合作。目前，30%的受邀演讲者要么是女性，要么是少数群体成员。一旦项目完成，从提交的摘要中挑选出来，我们预计至少有35%的女性和少数族裔演讲者，以及至少35%的早期调查人员(助理教授、博士后和/研究生)。预计将有350-450人参加，其中包括100-150名学生/博士后。报名不受限制，所有感兴趣的人都可以参加。将特别努力招募少数群体和工业参与者；鉴于巴尔的摩位于东海岸的中心地理位置，后者应该很容易实现。参与者将在每天下午展示关于新发现的海报。重要的是，这次会议为年轻研究人员提供了一个论坛，让他们看到基础科学研究与应用科学方法设计有效的人类疾病干预措施之间的联系。为强调这一目标，将选择28多个补充会议主题的海报发言作为简短的口头发言，并将过去几次会议的发言时间从10分钟增加到15分钟。最后，值得注意的是，在会议之前，US-HuPo提供了几个为期半天的关于蛋白质组学当代主题的短期课程。

DESCRIPTION (provided by applicant): We request partial funding support for operation of the 2013 Annual Meeting of the United States Human Proteome Organization (US-HUPO) entitled "Translational Proteomics: Biology, Technology and Clinical Advances", to be held March 10-13, 2013 in Baltimore, Maryland. Since the first US HUPO meeting in 2005, this venue has been and continues to be a vital conference for the highly interdisciplinary scientific field of proteomics, particularly as directed towards biological and clinical questions. US-HUPO is a unique meeting of scientists because it truly reflects the multidisciplinary interactions that have allowed proteomic researchers to approach and solve sophisticated biomedical problems. The US-HUPO meeting endeavors to promote the clinical application and translation of diverse technological platforms including mass spectrometry, protein microarrays, biosensors, clinical assays to biomarker discovery and validation for diagnostic, prognostic and treatment purposes. The US-HUPO conference is heavily attended and has always attracted first-rate speakers in this field. The 2013 Annual Meeting will again bring together an outstanding and diverse group of scientists at the forefront of proteomics. Invited speakers in the symposium will explicitly discuss applications relevant to a wide range of diseases including cardiovascular disease, cancer, and infectious diseases. As technological advances made in the recent years are of critical importance in enabling scientists to more effectively address biological problems, the technological future of proteomics will also be a hallmark of the meeting. The topics chosen will educate participants on the latest, most effective technologies and methods, illustrate successful translation of these technologies into the clinic, and highlight new directions and grand challenges for the future of this field. Interactive panel discussions will be held on key topics in order to encourage a robust dialogue between speakers and meeting participants to discuss critical goals for the future in proteomics, outline anticipated obstacles, and brainstorm solutions. This year US-HUPO will continue highly successful parallel Career Development sessions in Biology, technology and clinical advances, to provide early stage investigators with crucial insights into growth areas in proteomics and strategies for professional development. The poster sessions will also offer a more informal exchange of scientific ideas and advances. Ample time will be devoted to social venues for attendees to meet each other and establish new contacts and collaborations. Currently, 30% of the invited speakers are either women or members of minority groups. Once the program is completed with selections from submitted abstracts, we expect to have at least 35% women and minority speakers, and at least 35% early stage investigators (assistant professors, post-docs and/ graduate students). Attendance is expected to be 350-450 participants, including 100-150 students/post-docs. Registration is not restricted, and all interested persons may attend. A special effort will be made to recruit minorit and industrial participants; the latter should be readily achievable given the central geographic location of Baltimore in the East coast. Participants will present posters on new findings each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, over 28 poster presentations that complement the themes of the meeting will be selected for short oral presentations with an increased time to 15 minutes from 10 minutes during the past meetings. Finally, it is important to note that, preceding the meeting, US-HUPO offers several Half-Day short courses on contemporary topics in proteomics.