2013-2015 Bioenergetics Gordon Research Conference

描述（由申请人提供）：本提案要求部分支持Bioenergetics Gordon研究会议（GRC）（2次会议），该会议将于2013年6月23日至6月28日在Proctor学院举行，并于2015年夏季举行，地点尚未确定。生物能量学是影响衰老和广泛的主要人类疾病的基本细胞机制，包括癌症、神经变性和代谢紊乱。在2013年庆祝其成立50周年之际，Bioenergetics GRCs在了解其基本机制及其对日益扩大的人类疾病范围的影响方面见证，塑造和促进了一项显着的科学发展。该GRC的广泛和长期目标是促进一种综合方法，以扩大分子和细胞生物能量学在人类衰老和疾病背后的生理和病理过程中的作用。Bioenergetics GRC为了解线粒体能量转导和氧化磷酸化缺陷的后果提供了一个交流进展的场所。这些会议的具体目标是召集大约32位代表生物能量学研究关键领域的演讲者和讨论领袖，共有130多名参与者参加两次（2013年，2015年）为期五天的会议。2013年的计划将有八个会议，广泛讨论健康和疾病中生物能源系统的当前问题，包括适应，结构，功能，机制，超分子组织和新兴技术。此外，海报展示者简短的演讲和讨论环节将允许所有参与者对这些主题做出贡献。2015年，一个类似的项目将会实施

DESCRIPTION (provided by applicant): This proposal requests partial support for the Bioenergetics Gordon Research Conference (GRC) (2 conferences) to be held at Proctor Academy, June 23 - June 28, 2013, and in the summer of 2015 at yet to be determined site. Bioenergetics is a fundamental cellular mechanism affecting aging and a wide spectrum of major human disease, including cancer, neurodegeneration, and metabolic disorders. Celebrating its 50th anniversary in 2013, the Bioenergetics GRCs have witnessed, shaped and fostered a remarkable scientific development both in terms of understanding its basic mechanisms and its impact on an ever increasing scope of human disease. The broad and long term goal of this GRC is to promote an integrated approach for the expanding role of molecular and cellular bioenergetics in physiological and pathological processes that underlie human aging and diseases. The Bioenergetics GRC offers a venue to communicate progress toward an understanding of mitochondrial energy transduction and the consequences of defects in oxidative phosphorylation. The specific aims of these meetings will be to convene about 32 speakers and discussion leaders that represent critical areas of bioenergetics research with a total of over 130 participants for two (2013, 2015) five day conferences. The program in 2013 will feature eight sessions that broadly address current issues in bioenergetic systems in health and disease, including adaptation, structures, functions, mechanisms, supramolecular organizations, and emerging techniques. In addition, poster presenter short talks and discussion session will permit all participants to contribute to these topics. In 2015, a similar program will cover fundamental structural and mechanistic aspects of bioenergetic systems and place continued and increased emphasis on its role in aging, neurodegeneration, metabolic disease, and cancer. The significance of this application is that the Bioenergetics GRC is the premier international scientific meeting covering nearly all aspects in the continuously expanding field of bioenergetics. These conferences direct and propel a broad community of bioenergetics scholars by gathering premier senior and the most promising junior international scientists who represent the future leader in this field. They provide opportunities for graduate students and post-docs to present their work in poster format and exchange ideas with leaders in the field thus, nurturing the next generation of bioenergetics research leaders. The health relatedness of this application is that bioenergetics is a fundamental biological process that impacts nearly all facets of human health. Altered energy metabolism is causative for a significant number of inherited disorders and is involved in biological aging, neurodegeneration, cancer, metabolic diseases, etc.