2013 Phagocytes Gordon Research Conference and Seminar

描述(由申请人提供)：有关吞噬细胞的戈登研究会议(GRC)自1981年以来一直存在。第17届吞噬细胞GRC将于2013年6月9日至14日在新罕布夏州沃特维尔山谷度假村举行。虽然巨噬细胞和中性粒细胞在先天免疫中的核心作用早已被认识到，但这一领域仍在继续演变。因此，20年前的会议主要集中在吞噬细胞结构和功能的基本方面，例如阐明中性粒细胞颗粒的组成，发现NADPH氧化酶，而2013年的吞噬细胞GRC将是一个高质量介绍和深入讨论吞噬细胞生物学最新发现的论坛，将重点介绍我们对这些细胞的表型可塑性及其在调节适应性免疫反应、系统炎症和宿主防御中的作用，以及临床相关性(如吞噬细胞在癌症、关节炎和阿尔茨海默病中的作用，包括最近确定的治疗靶点)以及将吞噬体用作疫苗学工具的最新进展的理解。特色技术成果将包括先进的成像技术，用于分析中性粒细胞在体内的迁移，以及反向工程细胞内信息流，以了解细胞极性。这次会议来自世界各地的科学家小组，他们在细胞生物学、生物化学、分子遗传学、微生物学、免疫学和临床医学方面具有不同的背景。这次会议一直是研究巨噬细胞和中性粒细胞功能不同方面的研究人员之间传播信息和促进交流的重要场所，也为受训人员和年轻研究人员提供了一个一般性的教育论坛。约有150名科学家参加了这次GRC，2011年，约39%的科学家是研究生或博士后研究员。2013年GRC的计划包括9个环节，其中26位受邀演讲者将展示他们最新和最令人兴奋的未发表的发现。每一次会议都将由该领域的专家担任讨论领袖。为了保持传统，我们还计划挑选6-8名初级科学家根据提交的摘要进行简短的演讲。每堂课之后都会有充足的时间进行激烈的讨论。除了口述之外 除了介绍，我们预计将在会议上展示90张海报。这一多方面的计划将为各级科学家提供参与的机会，旨在促进 为了进一步促进学生和博士后研究员的参与和专业发展，2013年会议将包括戈登研究生研究研讨会(GRS)，该研讨会将于6月8日至9日举行，紧接着GRC开始之前，由实习生组织。头两次这样的GRCs是与2009年和2011年的吞噬细胞GRCs一起举行的，出席人数很多，也很受欢迎。我们预计2013年的上座率会更高。

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Phagocytes has been in existence since 1981. The 17th GRC on Phagocytes will be held June 9-14, 2013 at Waterville Valley Resort, Waterville Valley, New Hampshire. Although the central role of macrophages and neutrophils in innate immunity has long been recognized, the field continues to evolve. Thus, whereas conferences 20 years ago focused on fundamental aspects of phagocyte structure and function, such as elucidation of the composition of neutrophil granules, and discovery of the NADPH oxidase, the 2013 Phagocytes GRC will be a forum for high-quality presentations and in depth discussions of the most recent discoveries in phagocyte biology, and will highlight the latest advances in our understanding of the phenotypic plasticity o these cells, and their roles in modulation of the adaptive immune response, systemic inflammation and host defense, as well as clinical correlates such as the roles of phagocytes in cancer, arthritis, and Alzheimer's disease, including recently identified therapeutic targets, and the use of phagosomes as tools for vaccinology. Featured technological achievements will include advanced imaging techniques for analysis of neutrophil migration in vivo and reverse engineering intracellular information flow to understand cell polarity. The Conference draws from a world-wide group of scientists with diverse backgrounds in cell biology, biochemistry, molecular genetics, microbiology, immunology and clinical medicine. This meeting has consistently been an important venue for disseminating information and facilitating communication between investigators studying different facets of macrophage and neutrophil function, and also provides a general educational forum for trainees and young investigators. Approximately 150 scientists attended this GRC, and in 2011, ~39% of whom were graduate students or postdoctoral fellows. The program planned for the 2013 GRC includes nine sessions wherein 26 invited speakers will present their latest and most exciting unpublished findings. Each session will be chaired by discussion leaders who are experts in the field. In keeping with tradition, we also plan to select 6-8 junior scientists to present short talks based on submitted abstracts. Each lecture will be followed by ample time for vigorous discussion. In addition to oral presentations, we expect 90 posters to be displayed at the meeting. This multifaceted program will provide opportunities for participation of scientists at all levels and is designed to promote the participation of junior investigators, postdoctoral trainees and new investigators to the field To further promote the participation and professional development of students and postdoctoral fellows, the 2013 Conference will incorporate a Gordon Graduate Research Seminar (GRS) on June 8-9, immediately prior to the start of the GRC, that is organized by trainees. The first two such GRSs were held in association with the 2009 and 2011 Phagocytes GRCs and have been well attended and very well received. We anticipate even greater attendance in 2013.