Biennial Meeting of the Chlamydia Basic Research Society

描述（由申请人提供）：衣原体仍然是影响全球数亿人的重要病原体。作为沙眼的病原，沙眼原体是世界上最常见的可预防失明的原因。然而，也许衣原体最重要的影响是它作为性传播感染最常见的细菌原因，经常导致盆腔炎和随后的输卵管阻塞和妇女不孕。此外，肺炎支原体是社区获得性肺炎的主要病因，并与冠状动脉疾病有关。在兽医学领域，流产梭菌是导致羊流产的重要原因，具有重要的经济影响，而鹦鹉螺致病菌通常与人类潜在的严重呼吸道人畜共患感染有关。当前的技术，特别是基因组学技术，已经导致了衣原体与宿主细胞的分子和细胞相互作用的理解，这些相互作用影响了感染的发病机制和宿主对感染的反应，新的和令人兴奋的工作迅速爆发。衣原体基础研究学会成立的主要目标是在两年一次的会议上提供一个论坛，讨论衣原体和衣原体感染的基础研究。以前的五次会议平均有来自多达17个国家的253名与会者，会议取得了杰出的成功，这次会议现在被衣原体研究界视为介绍新的基础研究的主要论坛。该协会的一个主要目标是大力鼓励研究生和博士后研究员的参与。在过去的五届会议中，平均有43.2%的注册人是研究生和博士后。研究生和博士后研究员的成功纳入是通过仔细协商较低的酒店和设施成本，并通过从包括NIH在内的外部来源筹集资金来支持他们的费用来实现的。在过去的5次会议中，学员口头演讲的比例平均为61%，学员也优先选择平台演讲。因此，2013年会议的具体目标将是：1)鼓励和促进衣原体生物学和发病机制的基础研究；2)为从事衣原体基础生物学、发病机制和疫苗开发研究的科学家提供一个交流信息的论坛；3)通过鼓励年轻科学家积极参与会议，促进衣原体研究领域的发展。

DESCRIPTION (provided by applicant): Chlamydia continues to be a significant pathogen affecting hundreds of millions world-wide. As the etiologic agent of trachoma, C. trachomatis is the most common cause of preventable blindness in the world. However, perhaps the most significant impact of Chlamydia is in its role as the most common bacterial cause of sexually transmitted infection, often leading to pelvic inflammatory disease and subsequent tubal obstruction and infertility in women. In addition, C. pneumoniae is a major cause of community-acquired pneumonia and has been associated with coronary artery disease. In the veterinary world, C. abortus is a significant cause of ovine abortion and has an important economic impact, while the avian pathogen C. psittaci is often associated with potentially severe respiratory zoonotic infection in humans. Current technology, particularly genomics, has resulted in a rapid explosion of new and exciting work in the understanding of the molecular and cellular interactions of chlamydiae with their host cell which impacts the pathogenesis and host response to the infection. The Chlamydia Basic Research Society was founded with the primary goal of providing a forum to address basic research on chlamydiae and chlamydial infections at biennial meetings. Five previous meetings with an average of 253 attendees from as many as 17 countries have convened with outstanding success, and this conference is now viewed by the Chlamydia research community as the main forum for the presentation of new basic research. A major goal of the Society is also to strongly encourage the participation of graduate students and post-doctoral fellows. At the past five meetings, an average of 43.2% of the registrants was graduate students and post-doctoral fellows. The successful inclusion of graduate students and post-doctoral fellows was accomplished by carefully negotiating low hotel and facility costs and by supporting their expenses with funds that were raised from outside sources including NIH. Trainees are also given preference for platform presentations with an average of 61% of the oral presentations given by trainees over the last 5 meetings. Therefore the specific aims of the 2013 meeting will be 1) to encourage and promote basic research in chlamydial biology and pathogenesis, 2) to provide a forum for the exchange of information among scientists engaged in research on basic chlamydial biology, pathogenesis and vaccine development, and 3) to promote the development of young scientists in Chlamydia research by encouraging their active participation in the meeting.