Twelfth Annual AACR International Conference on Frontiers in Cancer Prevention Re

描述(申请人提供)：第十二届国际癌症预防研究前沿年会将于2013年10月27-30日在马里兰州国家港湾的盖洛德国家度假村和会议中心举行。AACR长期以来一直支持癌症预防研究，旨在通过改变生活方式和早期发现和治疗来预防癌症。这个一年一度的AACR会议系列会议于2002年首次亮相，至今仍是世界上最著名的癌症预防会议，在这个会议上，医生、科学家、患者和幸存者倡导者从该领域领先的基础、临床、流行病学和行为科学家那里了解最新的翻译发现。这次会议促进了跨学科合作，加快了预防研究领域的进展，并促进了人们对癌症预防在降低癌症发病率和死亡率方面的极端重要性的认识。今年的会议主题是“加速发现、翻译和应用”，将把焦点放在预防的力量上。科学进步正在改变癌症预防领域，为我们提供了所需的信息和技术，以了解人类癌症发生的分子基础，并以前所未有的准确性和有效性识别和干预疾病过程。通过加速新发现并将我们对基础科学的理解转化为临床应用，公共卫生层面正在看到好处。致癌起始和进展中的几个步骤是癌症预防的目标。初级预防是避免接触致癌物或致癌过程，可针对没有表现出癌前症状的广大个人。锻炼和避免吸烟就是这种干预的例子。最成功的初级预防策略之一是开发乙肝疫苗和人乳头状瘤病毒疫苗。二级预防工作正在受到关注，包括筛查和早期发现，这些工作通常针对更具体的风险人群。这类预防的例子包括结肠镜检查和息肉切除术。研究发现，癌前病变可能比以前认识到的更常见，了解哪些癌前病变进展为癌症，另一些不进展为癌症将是至关重要的。最后，三级预防的目的是防止复发或第二次癌症。

DESCRIPTION (provided by applicant): The Twelfth Annual International Conference on Frontiers in Cancer Prevention Research will take place October 27-30, 2013, at the Gaylord National Resort and Conference Center in National Harbor, Maryland. The AACR has long been a supporter of cancer prevention research aimed at preventing cancer through lifestyle changes and early detection and treatment. This annual AACR conference series debuted in 2002 and remains the pre-eminent cancer prevention meeting in the world, a place where physicians, scientists, patients, and survivor advocates learn about the latest translational discoveries from the leading basic, clinical, epidemiologic, and behavioral scientists in the field. The conference fosters interdisciplinary collaborations, accelerates progression in the field of prevention research, and promotes awareness of the vital importance and of cancer prevention in reducing cancer incidence and mortality. This year's conference theme, "Accelerating Discovery, Translation, and Application," will put the spotlight on the power of prevention. Scientific advances are transforming the field of cancer prevention by providing us with the information and technology needed to understand the molecular underpinnings of carcinogenesis in humans and to identify and intervene in disease processes with unprecedented accuracy and effectiveness. By accelerating new discoveries and translating our understanding of the basic science into clinical application, benefits are being seen at the public health level. Several step within carcinogenic initiation and progression are targets for cancer prevention. Primary prevention is the avoidance of exposure to carcinogens or the carcinogenic process and may be directed at the broad population of individuals who show no sign of premalignancy. Exercise and avoidance of tobacco are examples of this type of intervention. And one of the most successful primary prevention strategies is the development of vaccines such as those for HBV and HPV. Secondary prevention efforts are receiving attention and include screening and early detection, which are generally directed toward a more specified risk population. Examples of this type of prevention include colonoscopy and polypectomy. Studies have found that premalignant lesions may be more common than previously realized and it will be crucial to understand who some premalignant lesions progress to cancer and others do not. Finally, tertiary prevention is aimed at preventing recurrence or second cancers.