IGF::OT::IGF LASER-DRIVEN PROTON AND CARBON THERAPY
IGF::OT::IGF LASER-DRIVEN PROTON AND CARBON THERAPY
批准号:
8742678
负责人:
FINN O'SHEA
金额:
$29.99万
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-09-20 至 2014-06-19
关键词:
AccelerationAddressCancer PatientCarbonCarbon ionClinics and HospitalsIonsLasersMalignant NeoplasmsOpticsPatientsPerformancePhaseProtonsQuality of lifeRadiation OncologyRadiation therapySurvival RateSystemTechnologyTexasTreatment EfficacyUniversitiesaustinclinical applicationconditioningcostdesignimprovedinnovationnovelproton beamproton therapytechnology development
中文摘要
虽然强子疗法的卓越疗效已经被清楚地证明,但它对
癌症患者受到当前系统成本和规模的限制。拟议的项目旨在解决
这个问题是通过利用创新的激光驱动离子加速技术来开发一种
紧凑、廉价的质子治疗系统,最终可以适应碳的加速
离子。高强度,200-300 MeV激光驱动的质子束将用德克萨斯州的Petawatt进行演示
激光通过使用超薄CH2靶实现的几种新的加速机制。
辐射束技术公司、德克萨斯大学奥斯汀分校和加州大学洛杉矶分校辐射部
肿瘤学将合作设计用于提供质子治疗的治疗系统的概念设计,以及
最终碳治疗,性能足以临床应用,成本和
住在一个单人房间里。强子治疗的体积和成本的大幅减少将使拟议的
对于世界各地的医院和诊所来说,该系统是一个更现实的选择,从而扩大了患者池
这种治疗方法是可用的,并有可能提高癌症存活率以及
放射治疗患者的生活。
英文摘要
While the superior therapeutic efficacy of hadron therapy has been clearly demonstrated, its availability to
cancer patients is limited by the cost and size of current systems. The proposed project seeks to address
this problem by utilizing innovative laser-driven ion acceleration technology for the development of a
compact, inexpensive proton therapy system that can ultimately be adapted for the acceleration of carbon
ions. High-intensity, 200-300 MeV laser-driven proton beams will be demonstrated with the Texas Petawatt
Laser through the implementation of several novel acceleration mechanisms with ultrathin CH2 targets.
RadiaBeam Technologies, the University of Texas at Austin , and the UCLA Department of Radiation
Oncology will collaborate on the conceptual design of a treatment system for delivering proton therapy, and
eventually carbon therapy, with performance sufficient for clinical application at a fraction of the cost and
fitting in a single room. This major reduction in size and cost of hadron therapy will make the proposed
system a much more realistic option for hospitals and clinics worldwide, thus expanding the pool of patients
to which this treatment is available and potentially improving cancer survival rates as well as the quality of
life for radiotherapy patients.
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