Individualizing cytomegalovirus preventative strategies following solid organ transplantation: a precision medicine approach

巨细胞病毒(CMV)感染是导致实体器官移植后预后不良的重要因素。目前的预防策略在某种程度上是有效的，但对患者群体的治疗类似，而不是针对个人，因此许多患者得到了不必要的治疗&突破性疾病仍在发生。我们提出了一个研究计划，旨在使实体器官移植受者的CMV预防策略个体化，并纳入新的诊断测试。

Cytomegalovirus (CMV) infection is a significant contributor to poor outcomes following solid organ transplantation. Current preventative strategies are somewhat effective but treat groups of patients similarly rather than targeting the individual, so many patients are treated unnecessarily & breakthrough disease still occurs. We propose a program of research directed towards individualizing CMV prevention strategies in solid organ transplant recipients, incorporating new diagnostic tests.