Synthesis of Therapeutic Agents for Treatment of Infectious Diseases

这项工作的范围是在体外筛选或动物中测试所需数量的化合物的小规模合成，以及用于早期I期临床研究的化合物的大规模合成。一些化合物需要按照cGMP法规进行合成。该合同将提供资源，用于合成治疗艾滋病毒、结核病、肝炎和其他与NIAID研究议程相关的传染病的有前途的化合物。

The scope of this effort is small scale synthesis of compounds in quantities required for testing in either in vitro screens or animals, and large scale synthesis of compounds for early Phase I clinical studies. Some compounds will require synthesis in compliance with cGMP regulations. This contract will provide resources for the synthesis of promising compounds for the treatment of HIV, tuberculosis, hepatitis and other infectious diseases of relevance to the research agenda of NIAID.