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中文摘要
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描述(由申请人提供):在新罕布什尔州安多弗举行的2013年分子膜生物学戈登会议将涵盖细胞器生物学和膜运输的最新进展,包括蛋白质分泌、膜成形机制和脂质生物学、膜运输对正常发育的重要性以及病原体入侵细胞。在其近30年的历史中,该会议在理解细胞器在生物过程中的关键作用方面取得了巨大进展,如细胞生长,发育,信号转导和蛋白质降解。重要的是,膜运输途径的机制现在已经为许多家族性疾病和健康相关问题提供了见解。除了经典的细胞生物学方法外,结构生物学和先进的生物物理学方法在生物学这一领域的进展中发挥着越来越重要的作用。2013年会议将涵盖这些领域的最新重大进展和其他最新发现。会议计划将最佳平衡演示文稿,包括科学家在他们的职业生涯的早期阶段,包括在该领域代表性不足的团体的成员,以及既定的调查人员。已邀请32名特邀发言人参加会议,将从提交的摘要中再选出18名发言人。会议的总体目标是推进对分子膜生物学重要主题的认识,培养下一代科学家,他们将引领该领域进入重要的新前沿,并加强NIH赞助研究的未来。
英文摘要
DESCRIPTION (provided by applicant): The 2013 Molecular Membrane Biology Gordon Conference in Andover, New Hampshire will cover recent advances in organelle biology and membrane traffic, including protein secretion, membrane shaping mechanisms and lipid biology, the importance of membrane trafficking for normal development, and pathogen invasion of cells. Over its nearly 30 year history, this conference has contributed to and witnessed tremendous progress in understanding key roles of organelles in biological processes such as cell growth, development, signal transduction and protein degradation. Importantly, mechanisms underlying membrane trafficking pathways have now provided insights on numerous familial diseases and health related issues. In addition to classical cell biological approaches, structural biology and advanced biophysical methods play an increasingly important role in progress in this area of biology. Recent major advances in these areas and other late- breaking discoveries will be covered at the 2013 conference. The meeting program will optimally balance presentations to include scientists in the early stages of their careers, to include members of groups underrepresented in the field, as well as established investigators. Thirty-two invited speakers have been invited to participate in the conference and an additional eighteen speakers will be selected from submitted abstracts. The overarching goals of the meeting are to advance knowledge on significant topics in molecular membrane biology and to cultivate the next generation of scientists who will lead the field into important new frontiers, and strengthen the future of NIH sponsored research.
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