2013 Vascular Cell Biology Gordon Research Conference

描述(由申请者提供)：申请资助将于2013年1月27日至2月1日在加利福尼亚州文图拉举行的“血管细胞生物学”戈登研究会议。血管生物学是一门新兴学科，它为我们对大多数器官系统的理解提供了重要的见解。血管生物学研究已被转化为许多临床学科，如肿瘤学、内科和心脏病学。重要的是，目前的血管研究有望为癌症、缺血性心血管疾病、慢性炎症性疾病、糖尿病、先天性血管疾病和神经疾病等重要疾病带来新的疾病机制和新的治疗靶点。会议将涵盖一系列前沿话题，包括发育信号和血管畸形、遗传学和基因组学的前沿、气体和脂质中介信号的病理生物学、再生/干细胞生物学、基质和生物力学信号、细胞生物学前沿、新疗法和血管免疫学。会议将汇集代表各种学科、方法和系统的发言者、讨论者和与会者，从而促进跨学科的讨论和见解。会议规模小，气氛非正式，将促进讨论和互动。年轻的研究人员和受训人员将有足够的机会讨论科学，并与在各自领域处于领先地位的资深同事建立网络。我们对血管生物学调节机制的理解取得了重大进展，特别是对各种疾病的细胞间通信和血管紊乱的新见解，以及对治疗学现状的批判性分析，使这次会议特别及时，在科学上令人兴奋。

DESCRIPTION (provided by applicant): Funds are requested to support the Gordon Research Conference on "Vascular Cell Biology" to be held Jan 27- Feb 1, 2013 in Ventura, CA. Vascular biology is an emerging discipline which has provided important insights into our understanding of most if not all organ systems. Vascular biology research has been translated into many clinical disciplines such as oncology, internal medicine and cardiology. Importantly, current vascular research promises to lead to novel insights of disease mechanisms and novel therapeutic targets of important diseases such as cancer, ischemic cardiovascular diseases, chronic inflammatory diseases, diabetes, congenital vascular diseases and neurological conditions. The conference will cover a range of cutting-edge topics including developmental signals and vascular malformations, frontiers in genetics and genomics, pathobiology of gaseous and lipid mediator signals, regenerative / stem cell biology, matrix and biomechanical signaling, cell biological frontiers, novel therapeutics and vascular immunology. The meeting will bring together speakers, discussants and participants who represent a wide range of disciplines, approaches and systems- thus promoting interdisciplinary discussions and insights. The small size of the conference and the informal atmosphere will facilitate discussion and interactions. Young investigators and trainees will have ample opportunities to discuss science and to network with senior colleagues who are leaders in their fields. Major advances in our understanding of regulatory mechanisms in vascular biology, especially new insights into cell-cell communication and vascular disturbances in various diseases as well as critical analysis of the current state of therapeutics make this a particularly timely and scientifically exciting meeting.