Public Health Practice and Policy Core

PHPP核心的目标是通过与政策制定者，服务系统组织者和伦理学家合作，支持关于翻译，适应和采用经过科学检验的预防和治疗干预措施到社区提供系统和其他公共卫生环境的研究，最大限度地发挥艾滋病毒中心有效干预措施的影响。自从艾滋病毒开始 随着艾滋病的流行，科学家们已经开发出基于证据的艾滋病毒预防干预措施，早期识别艾滋病毒病例，及时参与和保留护理，以及坚持抗逆转录病毒治疗（ART），通常，进展来自随机对照试验，然而，广泛采用和明显的基于人群的健康改善已被证明具有挑战性。在学术孤立的情况下开发的干预措施往往无法解决现实世界的制约因素--资源不足， 劳动力能力;资金和政策分散;此外，伦理困境和滞后的政策阻碍了循证干预措施的及时采用，不断变化的流行病对一线临床医生提出了新的挑战，学术研究人员迟迟未能解决。鉴于生物行为预防和治疗方法的预期快速进展可能在未来五年内成为流行病， 中心已选择将转化研究和实施科学作为高度优先事项。我们的目标是优化我们的循证干预措施在实践环境中的推广，并利用证据为医疗保健政策和服务提供组织提供信息[3-5]。 PHPP核心是从目前的两个艾滋病毒中心核心，全球社区核心（GCC）和道德和政策核心发展而来的。这个新的核心将建设转化研究和实施科学的能力，提供先进的道德和人权咨询，并将最终用户，政策制定者，交付组织领导和研究人员团结在一个持续的伙伴关系中，以应对实施挑战。PHPP核心将专门致力于缩小科学、政策和艾滋病毒之间的差距 预防和护理服务。

The goal of the PHPP Core is to maximize the impact of HIV Center efficacious interventions by supporting research on the translation, adaptation, and adoption of scientifically tested prevention and treatment interventions into community-based delivery systems and other public health settings by partnering with policy makers, service system organizers, and ethicists. Since the beginning of the HIV epidemic, scientists have developed evidence-based interventions for HIV prevention, earlier identification of HIV cases, timely engagement and retention in care, and adherence to antiretroviral therapy (ART), Typically, advances emerge from randomized controlled trials, however, widespread adoption and demonstrable population-based health improvement has proved challenging. Interventions developed in academic isolation often fail to address real-world constraints - insufficient resources and workforce capacity; fragmented funding and policies; and tensions among recipients, providers, policy makers, and researchers [1,2], In addition, ethical dilemmas and lagging policy hinder timely adoption of evidence-based interventions, and the changing epidemic poses new challenges to front-line clinicians that academic researchers are slow to address. In light of the expected rapid advances in biobehavioral prevention and treatment approaches likely to emerge as the epidemic over the next five years, the HIV Center has chosen to make translational research and implementation science a high priority. We aim to optimize the scale-up of our evidence-based interventions into practice settings and the use of evidence to inform health care policy and service delivery organization [3-5]. The PHPP Core has evolved from two current HIV Center cores, the Global Community Core (GCC) and Ethics and Policy Core. This new Core will build capacity in translational research and implementation science, provide sophisticated ethics and human rights consultation, and unite end users, policy-makers, delivery-organization leadership, and researchers in an ongoing partnership to address implementation challenges. The PHPP Core will specifically aim to close the gaps among science, policy, and HIV prevention and care services.