Biometrics

项目总结(见说明)： 生物统计学核心(前身为生物统计核心)提供的基础设施有助于华盛顿大学(UW)和弗雷德·哈钦森癌症研究中心(FHCRC)对艾滋病毒/艾滋病研究中的统计数据采取有组织、协同和集中的方法。特别是，核心为CFAR调查人员提供设计、进行和分析临床研究和实验室研究方面的先进统计方法和专业知识。生物识别核心还在CFAR生物医学研究人员与华盛顿大学和弗雷德·哈钦森癌症研究中心的大量生物统计学和其他定量科学教员之间提供了重要的联系，他们正在为艾滋病毒/艾滋病研究开发新方法。使用Core的CFAR临床、行为和实验室研究人员提供用于分析的数据集，这些数据集推动了华盛顿大学和FHCRC的生物统计学家、生物数学家、工程师和计算机科学家开发新的定量方法。因此，这种联系使CFAR研究人员和学术定量科学研究人员受益。 为了促进和促进这些多学科互动，生物识别核心：1)就研究设计、表格设计、评估和预测试、数据分析、解释和报告提供统计和数学协作和咨询；协调数据安全和监测委员会；提供数据管理服务；维护可供任何CFAR调查员使用的计算设施(现场和远程登录)；2)赞助和开展旨在向CFAR调查人员传播统计技能的培训活动，告知艾滋病毒/艾滋病研究人员生物识别核心提供的服务，并将新的量化方法引入UW/FHCRC CFAR社区，3)作为具有高级量化需求的核心用户与UW生物统计、统计、数学和应用数学部门的专家以及FHCRC生物统计和生物数学计划之间的联络人；4)根据需要开发、调整和/或实施新的或新的统计和数学方法；和5)组织活动，促进现有统计人员之间在艾滋病毒/艾滋病研究方面的交流，并吸引其他生物统计人员的兴趣，以满足日益增长的艾滋病研究需求。

PROJECT SUMMARY (See instructions): The Biometrics Core (formerly the Biostatistics Core) provides the infrastructure that facilitates an organized, synergistic, and centralized approach to statistics in HIV/AIDS research at the University of Washington (UW) and the Fred Hutchinson Cancer Research Center (FHCRC). In particular, the Core provides advanced statistical methods and expertise in the design, conduct and analysis of clinical research and laboratory studies to CFAR investigators. The Biometrics Core also provides a crucial link between CFAR biomedical researchers and the large number of biostatistics and other quantitative sciences faculty at the University of Washington and the Fred Hutchinson Cancer Research Center who are developing new methods for HIV/AIDS research. The CFAR clinical, behavioral, and laboratory researchers using the Core provide datasets for analysis which motivate the development of new quantitative methods by biostatisticians, biomathematicians, engineers and computer scientists at UW and FHCRC. Hence, this link benefits CFAR investigators as well as academic quantitative science researchers. To promote and facilitate these multidisciplinary interactions the Biometrics Core: 1) provides statistical and mathematical collaboration and consultation on study design, forms design, evaluation and pre-testing, data analysis, interpretation and reporting; coordinates Data Safety and Monitoring Boards; provides data management services; maintains computing facilities that are available (both on site and by remote login) to any CFAR investigator; 2) sponsors and conducts training activities designed to disseminate statistical skills to CFAR investigators, inform the HIV/AIDS researchers about services available from the Biometrics Core, and introduce novel quantitative approaches to the UW/FHCRC CFAR community, 3) serves as a liaison between the Core user with advanced quantitative needs and experts from the UW Departments of Biostatistics, Statistics, Mathematics, and Applied Mathematics, and the FHCRC Program in Biostatistics and Biomathematics; 4) develops, adapts and/or implements new or novel statistical and mathematical methods as needed; and 5) organizes activities that promote communication among existing statisticians in HIV/AIDS research and interest from other biostatisticians that can be recruited to meet the growing demand of AIDS research.