STUDY OF EFFECTS OF ASPIRIN IN GESTATION AND REPRODUCTION (EAGeR) TRIAL

该合同的目的是使NICHD流行病学、统计和预防研究司能够开展各种研究，重点是对男子、妇女和儿童的一系列健康影响，这些研究依赖于对血液、尿液、脂肪组织、卵泡或精液等生物样本中浓度的定量。承包商将分析各种库存标本的激素水平，饮食生物标志物和代谢功能指标的个人浓度。该司对一系列标志物感兴趣，但优先事项包括：抗苗勒管激素、维生素B B、雄激素、瘦素和咖啡因。此外，自然产生的植物雌激素和代谢物也是该司研究的兴趣所在。

The purpose of this contract is to enable the NICHD Division of Epidemiology, Statistics and Prevention Research (DESPR) to conductsvarious studies focusing on a spectrum of health effects in men, women, and children, which rely upon quantification of concentrations in biologic specimens such as blood, urine, adipose tissue, follicular or seminal fluids. The contractor will analyze a variety of banked specimens for individual concentrations of hormone levels, dietary biomarkers, and indicators of metabolic function. A range of markers are of interest to the Division, though priorities include: anti-m¿llerian hormone, inhibin B, androgens, leptin, and caffeine. In addition, naturally occurring phytoestrogens and metabolites are also of interest to the Division¿s research.