Core A: Administration and Biostatistics

项目摘要 行政和生物统计核心将提供集中的赠款管理，通信，数据 项目的共享和统计分析。这一核心也有助于合并调查人员，他们的 实验发现及其思想，促进转化工作，并直接努力实现计划目标 和结果。此外，该核心的生物统计学和数据集成部分将创建和运行一个 用于交换数据、通信和评估计划进展的安全网站。具体 目标包括： 目标1.为调查人员提供基本行政服务。 服务包括管理供应品、归档、备忘录、会议记录和 通信覆盖所有业务。核心将为研究人员提供清晰的科学和 行政沟通，以促进合作，帮助资源的优先次序，并促进 解决任何影响团队成员的问题。 为研究者提供与项目相关的通信出版服务。 目标2.为所有项目提供数据管理和统计分析。 与项目研究人员合作制定假设和研究设计。 进行和指导数据的统计分析，包括描述性汇总统计和 复杂的推理程序 及时审查、质量保证和传播调查结果。 安装数据优先级评估和机构间安全网站，用于共享和存储 数据库。提供对数据集的实时访问和数据集的标准化， 来自所有机构的管理人员对统计数据和直接建模和实验设计提供投入。 目标3。组织科学和咨询委员会会议 每月指导委员会会议（项目负责人、核心董事和主要工作人员）。 每周PPG逆转录病毒学实验室科学数据会议（所有项目成员及其实验室） 内部和外部科学咨询委员会（ISAB和ESAB）年度会议。专家小组 应评估该计划的有效性和实验进展，研究方向，统计 评估和管理效率。每个委员会将审查实验结果和翻译 结果，帮助优先调查，审查合作，并评估出现的概念。 目标4。提供全面的财务审查，会计和真实的时间预算分析。

PROJECT SUMMARY The Administration and Biostatistics Core will provide centralized grant administration, communications, data sharing, and statistical analyses for the projects. This Core also serves to amalgamate the investigators, their experimental findings and their ideas, promote translational efforts and direct efforts toward the Program goals and outcomes. In addition, the Biostatistics and Data Integration part of this core will create and operate a secure web site for the interchange of data, communications, and the evaluation of Program progress. Specific Aims include: Aim 1. Provide basic administrative services to the investigators. ¿ Service includes the management of supplies, filing, development of memos, meeting minutes and communications covering all operations. The Core will provide investigators with clear lines of scientific and administrative communication to promote collaboration, aid in the prioritization of resources, and facilitate resolution of any problems that affect team members. ¿ Provide publication services to the investigators for project-related communications. Aim 2. Provide data management and statistical analyses for all projects. ¿ To collaborate with project investigators in the formulation of hypotheses and study design. ¿ To conduct and direct the statistical analysis of data including both descriptive summary statistics and sophisticated inferential procedures. ¿ Provide timely review, quality assurance, and dissemination of the results gleaned from investigations. ¿ To install data prioritization evaluation and an inter-institutional secure website for sharing and storing databases. Provide access in real-time to data sets and standardization of data sets to permit data managers from all institutions to have input on statistics and direct modeling and experimental design. Aim 3. Organize Scientific and Advisory Board Meetings ¿ Monthly Steering Committee Meetings (Project Leaders, Core Directors, and key staff members). ¿ Weekly PPG Retrovirology Laboratory Scientific Data Meetings (all project members and their labs) ¿ Annual Internal and External Scientific Advisory Board (ISAB & ESAB) meetings. Panel of experts shall assess the Program effectiveness and experimental progress, research directions, statistical evaluation, and admin effectiveness. Each board will review experimental findings and translational outcomes, help prioritize investigations, review collaborations, and evaluate concepts that emerge. Aim 4. Provide overall fiscal review, accounting, and real time budgets analyses.