Multidisciplinary Studies of Hematopoietic Malignancies

1.我们完成了对主要病例对照研究的分析，并在同行评审期刊上发表了约50份报告。 2.我们证明了风险的模式根据淋巴瘤的亚型而不同。 3.我们发现NHL发生的遗传危险因素也能预测生存率;我们将继续探索其他亚型以比较病因和生存率的模式。 4.为了进行GWAS并更有效地研究遗传多态性，我们正在Interlymph中汇集数据。5.我们继续与InterLymph合作，并报告了超重、阳光、丙型肝炎病毒、染发剂和生殖史的汇总估计值。6.我们将其他来源的环境数据与研究数据相结合，继续调查环境风险。这项工作正在进行中。

1. We completed analysis of the main case-control study and published approximately 50 reports in peer-reviewed journals. 2. We demonstrated that the patterns of risk vary according to the subtype of lymphoma. 3. We showed that genetic risk factors for occurrance of NHL also predicted survival; We're continuing to explore other subtypes to compare the patterns of etiology and survival. 4. To conduct a GWAS and to study the genetic polymorphism with more power, we are pooling data within Interlymph. 5. We continued to collaborate with InterLymph and we reported on the pooled estimates for overweight, sunlight, hepatitis C virus, hair dyes, and reproductive history. 6. We combined environmental data from other sources with study data to continue to investigate environmental risks. This work is ongoing.