THE SYNTHESIS AND PRECLINICAL STUDIES OF NEW TREATMENTS FOR NEURODEGENERATIVE DISEASE, DIABETES MELLITUS, CONGESTIVE HEART FAILURE, ONCOLOGIC AND IMMUNOLOGIC DISEASES

这是一份支持NIA工作人员与SRI工作人员之间互动的一般合同，涉及： 1.参加与承包商的技术代表（COTR）的定期电话会议以及SRI项目内部会议，以讨论合同的整体执行和进展情况; 2.根据基础合同的要求，编制并提交月度技术进展报告和年度进展报告; 3.为COTR和NIA提交研究者提供未来和待分配研究的非临床/临床前开发咨询服务，包括文献研究，以确定具体的研究要求和范围。这些活动通常包括反复讨论和向COTR和提交研究者提供书面初步研究大纲，以确定具体的研究需求;以及 4.存档GLP监管研究的保留成本。

This is a general contract to support interactions between NIA staff and those of SRI in relation to: 1. Participation in regular teleconferences with the Contracting Officer’s Technical Representative (COTR) as well as internal SRI project meetings to discuss overall contract implementation and progress; 2. Preparation and submission of Monthly Technical Progress Reports and Annual Progress Reports as required by the base contract; 3. Provision of nonclinical/preclinical development consultation services to the COTR and NIA Submitting Investigators on future and to-be-assigned studies, including literature research to determine specific study requirements and scope. These activities usually include iterative discussions and provision of written preliminary study outlines to the COTR and Submitting Investigator to define specific study needs; and 4. Retention costs of archived GLP-regulated studies.