NANOTOX 2014, 7th International Nanotoxicology Congress

描述(由申请人提供)： 纳米技术的最新进展已经彻底改变了生活的方方面面，从工程、半导体、建材到化妆品和纳米医学。独特的物理化学特性加上巨大的表面积，使得纳米材料的生物效应及其与细胞、组织和生物体液的相互作用在很大程度上是不可预测的。越来越多的工程纳米材料的使用引起了人们对无意中接触这些材料以及可能对人类健康和环境产生不利影响的担忧。因此，一个新的爆炸性发展的毒理学领域--纳米毒理学--应运而生。纳米毒理学领域的实验工作正在以指数速度进行。尽管如此，关于纳米材料对人类健康和包括自然生态系统在内的环境的潜在影响的数据仍然基本缺乏。填补这一知识空白将需要科学组织、监管机构和利益相关者之间空前程度的国家和国际协调。拟议的纳米毒理学-2014国际会议是朝着这一方向迈出的重要一步。2014年国际纳米毒理学会议将于2014年4月23日至26日在土耳其安塔利亚举行，届时将汇集纳米材料毒理学领域的当前研究带头人，从材料科学家、化学家和制造商到分子毒理学家、风险评估专家以及参与纳米颗粒生物医学应用的临床医生和翻译科学家。自2006年在美国(迈阿密)发起并组织了第一届国际纳米毒理学会议以来，在苏黎世(2008年)、爱丁堡(2010年)和北京(2012年)举行了一系列半年一次的会议。这些会议代表了纳米毒理学领域的重大科学事件，在这些事件中，这一新兴学科的最具创新性和重大突破性成果得到了战略性传播，并向科学家研究界、纳米材料制造业的代表、公共卫生官员和风险评估/监管问题专家提供了信息。会议的主要目标是为具有不同专业领域的调查人员创造跨学科讨论的机会，以共同了解 纳米材料的化学、生物学、分子作用机制和毒性，从而为风险评估提供依据，从而促进纳米材料的设计和生产，将对人类健康和环境的不利影响降至最低。会议的主题集中在纳米毒理学爆炸性学科的最新创新领域：纳米毒理学和人类毒理学，纳米环境健康和安全，生态-纳米毒理学，剂量-反应范式，无毒的分子机制，对纳米颗粒的免疫反应，纳米医学，药代动力学和偏心动力学，纳米生物界面和纳米生物材料，纳米材料的暴露情景和风险评估，系统生物学方法，纳米安全，在Silico建模方法中，包括纳米QSARs，纳米技术风险的监管挑战。面向青年研究人员的《纳米安全研究方法》系列讲座也将列入大会日程。两个特别圆桌讨论会将集中讨论纳米安全领域的全球战略研究议程。总体而言，会议的议题将涉及与环境、职业和生物医学暴露于纳米材料有关的关切问题相关的主要研究方向。这次会议将为与会者创造机会，与来自全球各地的纳米毒理学领域的专家介绍和分享经验，探索新的方向和辩论主题。

DESCRIPTION (provided by applicant): Recent advances in nanotechnology have revolutionized all aspects of life, from engineering, semiconductors, building materials to cosmetics and nanomedicine. The unique physico-chemical characteristics combined with the vast surface area make the biological effects of nano-materials and their interactions with cells, tissues and biofluids largely unpredictable. The increasing use of engineered nanomaterials raises concerns about inadvertent exposure to these materials and the potential for adverse effects on human health and the environment. As a result of this, a new and explosively developing field of toxicology - nanotoxicology - has emerged. Experimental work in the field of nanotoxicology is progressing at exponential rate. In spite of this, there is still a fundamental lack of data on the potential impacts of nanomaterials n human health, and the environment, including natural ecosystems. Filling this gap of knowledge will require an unprecedented degree of national and international coordination between scientific organizations, regulatory agencies, and stakeholders. The proposed International Conference Nanotoxicology-2014 is an important step in this direction. The International Conference Nanotoxicology-2014 - to be held in Antalya, Turkey from April 23 through 26, 2014 - will bring together current research leaders in the field of toxicology of nanomaterial's from material scientists, chemists and manufacturers to molecular toxicologists, risk assessment experts as well as clinicians and translational scientists involved in biomedical applications of nanoparticles. Since 2006, when the first International conference on nanotoxicology has been initiated and organized in the US (Miami), a series of bi-annual meetings was conducted in Zurich (2008), Edinburgh (2010), and Beijing (2012). These conferences represented the major scientific events in the field of Nano toxicology whereby most innovative and significant breakthrough results in the emerging discipline were strategically disseminated and made available for the research community of scientists, representatives of nanomaterial's manufacturing industries, public health officials and experts in risk assessment/regulatory issues. The primary goal of the conference is to create the opportunity for cross disciplinary discussions for investigators with different fields of expertise working together to understand the chemistry, biology, molecular mechanisms of action and toxicity of nanomaterial's, hence to provide basis for risk assessments thus facilitating the design and production of nanomaterial's with minimized adverse effects on human health and the environment. The topics of the conference are focused on the latest most innovative areas of the exploding discipline of nanotoxicology: nanotoxicology and human toxicology, nano-environmental health and safety, eco-nanotoxicology, dose-response paradigm, molecular mechanisms of nontoxicity, immune responses to nanoparticles, nanomedicine, pharmacokinetics and particokinetics, nano-bio interface and nanobiomaterials, exposure scenarios and risk assessment of nanomaterials, systems biology approaches to nanosafety, In Silico modeling approaches including nano-QSARs, regulatory challenges of nanotechnology risks. A series of lectures on "Methods in nanosafety research" for young investigators will also be included in the program of the conference. Two special round-table discussions will be focused on the world-wide strategic research agenda in the field of nanosafety. Overall, the topics of the conference will address the major directions of research relevant to concerns associated with the environmental, occupational and biomedical exposures to nanomaterials. The conference will create opportunities for participants to present and share experiences, explore new directions and debate topics with experts from across the globe in the field of nanotoxicology.