CADENCE-KIDS: Cadence and Intensity in Children and Adolescents

描述（由申请方提供）：Cadence-Kids是一项R21探索性/发展性研究，旨在1）测量6-20奥尔兹年龄段的节奏（步/分钟）并将其与强度临界点联系起来，2）使用这些临界点描述儿童和青少年在自由生活中的行为。步频是步态的时空参数之一。步频乘以步幅等于速度。捕捉和表达的体力活动的节奏是一个被忽视的机会，检查自由生活模式的走动强度。为了实现我们的主要目标，我们将确定并招募10名儿童和青少年（5名男孩，5名女孩） 从6-20岁之间的每个年龄年（总共150名儿童和青少年的10个年龄年的跨度）到基于实验室的节奏研究（在跑步机上评估），然后是为期一周的习惯性身体活动的自由生活研究。在实验室条件下， 不同踏车频率的间接测热法。随后，我们将监测这些人的习惯性每分钟的节奏一周。我们假设儿童的强度将随着节奏的线性或非线性增加而增加，这样我们就能够开发新的统计模型来预测节奏强度的标记（切割点）。我们进一步假设，与从更通用的活动计数切割点获得的结果相比，使用性别和年龄校准的节奏结果，儿童在至少中等强度活动中的时间的自由生活估计将更高。我们在彭宁顿生物医学研究中心的独特地位，成功地进行Cadence儿童设计在2年的时间内。我们已经建立了招聘方法，与学校和社区建立了良好的联系，并且在运动测试和加速度测量方面经验丰富。从这项R21探索性/发展性研究中获得的信息将为未来与节奏相关的R 01研究提供信息，节奏是确定儿童自由生活体力活动健康水平的强度指标。如果成功的话，我们预计节奏切割点将用于评估步行强度，而且还可以告知程序设计，不仅关注增加身体活动量（例如，步数/天）而且其强度（例如， 节奏）在用户友好的指标。

DESCRIPTION (provided by applicant): Cadence-Kids is an R21 exploratory/developmental study designed to 1) measure and link cadence (steps/minute) to intensity cut points across age in 6-20 year olds, and 2) describe children's and adolescents' behavior in free-living using these cut points. Cadence is just one of the temporal-spatial parameters of gait. Cadence multiplied by stride length equals speed. Capture and expression of physical activity in terms of cadence represents an overlooked opportunity to examine free-living patterns of ambulatory intensity. To achieve our primary aim, we will identify and recruit 10 children and adolescents (5 boys, 5 girls) from each age-year between 6-20 years (a span of 10 age-years for a total of 150 children and adolescents) to a lab- based study of cadence (assessed on a treadmill) followed by a week-long free-living study of habitual physical activity. Under laboratory conditions we will calibrate different treadmill cadences with indirect calorimetry. We will subsequently monitor these same individuals' habitual minute-by-minute cadence for one week. We hypothesize that children's intensity will increase as cadence increases in a linear or nonlinear fashion such that we will be able to develop novel statistical models for predicting markers (cut points) of intensity from cadence. We further hypothesize that free-living estimates of children's time in at least moderate intensity activity will be higher using sex and age-calibrated cadence results compared to that obtained from more generic activity count cut points. We are uniquely positioned at the Pennington Biomedical Research Center to successfully conduct Cadence Kids as designed in a 2-year time period. We have established recruiting methods, excellent connections with schools and the community, and are fully experienced in exercise testing and accelerometry. The information derived from this R21 exploratory/developmental study will inform future R01 investigations related to cadence as an indicator of intensity in determining healthful levels of children's free-living physical activity. If successful, we expect that cadence cut points will be used both to assess ambulatory intensity, but also to inform program design focused on increasing not only the volume of physical activity (e.g., steps/day) but also its intensity (e.g., cadence) in user-friendly metrics.