Fragile Families and Child Wellbeing in Adolesence

脆弱家庭和儿童福利研究（FFS）是一项具有全国代表性的出生队列研究，研究对象为1998年至2000年间在美国大城市（人口20万或以上）出生的约4900名儿童。该研究包括：（1）在孩子出生时以及在孩子1岁、3岁、5岁和9岁时再次采访母亲和父亲，（2）出生时母亲和孩子的医疗记录，（3）在孩子3岁、5岁和9岁时对孩子及其家庭环境的家庭评估，（4）在孩子9岁时采访孩子，（5）在孩子3岁时采访老师，5岁和9岁，（6）9岁时母亲和孩子的DNA样本。这项研究还包括在孩子出生后的头四年里对大约75对夫妇进行深入的纵向访谈。研究设计要求对未婚父母的出生进行大量的过度抽样，因此这些数据是研究少数民族和经济弱势群体之间健康差异的宝贵资源。到目前为止，已有1300多名研究人员下载了公共使用数据，Google Scholar列出了2006-2011年NICHD资助期间使用FFS数据的730篇学术文章，论文，书籍和摘要。我们寻求资金，以便在儿童15岁时对母亲和儿童进行另一轮采访。我们的具体目标是：“更新关于儿童健康和发展的信息，并收集关于儿童15岁时的健康和健康风险行为、学校表现以及反社会和亲社会行为的新数据“更新关于儿童15岁时的背景因素的信息，包括家庭、社区、学校和同龄人，包括自上次访谈以来家庭经历的回顾性数据“ 收集3600名15岁儿童的唾液样本，用于未来的甲基化分析。将通过电话采访大约3600名母亲和3100名儿童。这些电话采访将是55分钟的母亲和45分钟的儿童。将对500名青少年进行约1小时的面谈。

DESCRIPTION (provided by applicant): The Fragile Families and Child Wellbeing Study (FFS) is a nationally representative, birth cohort study of approximately 4900 children born in large US cities (populations of 200,000 or more) between 1998 and 2000. The study includes: (1) interviews with mothers and fathers at birth and again when children are 1, 3, 5 and 9 years old, (2) medical records for a subset of mothers and children at birth, (3) in-home assessments of children and their home environments when children are 3, 5, and 9 years old, (4) interviews with children at age 9, (5) interviews with teachers when children are 3, 5, and 9 years old and (6) DNA samples from mothers and children when children are age 9. The study also includes in-depth, longitudinal interviews with a subset of approximately 75 couples during the first four years after the child's birth. The study design called for a large oversample of births to unmarried parents, and thus the data are a valuable resource for studying health disparities among minority and economically disadvantaged populations. To date, more than 1300 researchers have downloaded the public use data, and Google Scholar lists 730 scholarly articles, theses, books, and abstracts using the FFS data for the period covered by the current NICHD grant, 2006-2011. We seek funding to conduct another round of interviews with mothers and children when children are 15 years old. Our specific aims are to: " Update information on children's health and development and collect new data on health and health risk behavior, school performance, and anti- and pro-social behavior when children are age 15 " Update information on contextual factors, including families, neighborhoods, schools and peers, when children are age 15, including retrospective data on family experiences since the last interview " Collect saliva samples from 3,600 children at age 15 to be used for future methylation analysis Approximately 3600 mothers and 3100 children will be interviewed via phone. These phone interviews will be 55 minutes for mothers and 45 minutes for children. Five hundred adolescents will be interviewed in person for approximately 1 hour.