UCSF/UCB Joint Graduate Group in BIoengineering

描述（由申请人提供）：本提案旨在为UCSF/UCB生物工程联合研究生小组（JBBG）的学生提供前两年的培训补助金和相关支持。在过去的25年里，JBBG已经向221名学生颁发了生物工程博士学位，其中86名学生获得了NIH培训补助金奖的津贴。这种津贴是JGGB独特结构的支柱，该结构要求学生在头两年获得经济支持。最初两年的准备工作包括工程和生物医学科学的密集课程，以及三次实验室轮转，这对学生选择合适的论文研究主题至关重要。在以后的一年里，学生们通过他们的研究导师获得经济支持。JGGB连接了加州大学两个具有互补优势的校区：加州大学旧金山分校是领先的健康科学机构，加州大学伯克利分校的工程学院是物理科学领域的全国领导者。为学生提供的培训环境的广度和深度是单一部门无法提供的。来自25个系的170多名教师参加了JGGB。他们的实验室拥有一系列最先进的设备。一个学术和智力环境促进物理和生命科学之间的无缝互动，培养学生解决复杂的生物问题，强调转化研究是高需求的。JGGB在这种整合方面有着良好的记录，广泛的合作机会是该计划的结构之一，让学生花两年时间专注于各种实验室轮转和课程工作，然后再致力于他们的论文项目。随着最近UCSF和UCB生物工程研究和教育项目的扩张，研究生的培养能力有所增加，学生人数从148人增加到173人。这项培训补助金是向学生提供的一揽子支助的一个重要组成部分，因此，它对于确保他们在目前竞争激烈的环境中茁壮成长变得越来越重要。由于合格的申请者远远超过了可以被JGGB录取的学生数量，我们要求在下一个资助周期将名额从目前建议的17名增加到25名。生物工程师整合不同领域的原理，从而跨越基础科学和临床应用进步之间的差距的独特能力，使在该领域受过培训的个人处于推进转化研究议程的关键点，这一议程最近被NIH内的新组织所强调。

DESCRIPTION (provided by applicant): This proposal aims to secure training grant stipends and associated support for students during their first two years in the UCSF/UCB Joint Graduate Group in Bioengineering (JBBG). Over the past 25 years, the JBBG has awarded Ph.D.s in Bioengineering to 221 students, with 86 of these receiving stipends from this NIH Training Grant Award. Such stipends are the backbone for the unique JGGB structure, which requires that students have financial support during their first two years. These initial two years of preparation include intensive course work in engineering and the biomedical sciences, as well as three laboratory rotations, are essential to the students in selecting appropriate dissertation research topics. In later year the students receive financial support through their research mentor. The JGGB bridges two University of California campuses that possess complementary strengths: UCSF is a leading Health Sciences institution and UC Berkeley's Engineering School is a national leader in the physical sciences. The breadth and depth of the training environment offered to students is of an order larger than a single department could provide. Over 170 faculty based in 25 departments participate in the JGGB. Their laboratories include an array of state-of-the art facilities. An academic and intellectual environment fosters seamless interaction between physical and life sciences and that trains students to solve complex biological problems with an emphasis on translational research is in high demand. The JGGB has an established record of such integration, and the breadth of opportunity for collaboration is one of the reasons that the program is structured to have students spend two years concentrating on a variety of laboratory rotations and course work prior to committing to their dissertation project. With the recent expansion of Bioengineering research and educational programs at UCSF and UCB, the capacity for training graduate students has increased and the size of the student body has grown from 148 to 173. This training grant is a critical component of the support package that students are offered, and it has therefore become increasingly important for ensuring that they flourish in the present competitive environment. Because qualified applicants far exceed the number of students that can be admitted into the JGGB, we are requesting an increase in the number of slots during the next funding cycle from the current recommended level of 17 to 25 students. The unique ability for bioengineers to integrate principles from diverse fields and thereby span the gap between advances in basic science and clinical utilization places individuals trained in this field at a critical point in advancing a translational research agenda that has been recently highlighted by new organizations within the NIH.