Fourth Pan American Dengue Research Network Meeting

 说明(申请人提供)：DENV被认为是最重要的新出现的人类虫媒病毒，在全球热带地区分布，每年导致约5000万登革热(DF)病例、75万例严重登革出血热和登革休克综合征(DHF/DSS)和约21,000人死亡。根据世界卫生组织的说法，在一些亚洲和拉丁美洲国家，严重的登革热是导致儿童严重疾病和死亡的主要原因。2013年，世卫组织仅在美洲就报告了235万例登革热病例，其中37687例是严重登革热。登革热研究领域在过去十年中显示出相当大的扩展，出现了新的候选疫苗，对疾病决定因素有了更好的了解，在诊断、预后和探索性治疗方面也取得了新的进展。然而，目前还没有特效治疗方法，也没有有效的疫苗。泛美登革热研究网络会议(泛登革网)是一项倡议，每两年召集美洲各地的研究人员讨论他们在该领域的最新进展，向该地区的科学界传达这一信息，促进团体之间的合作，并讨论进一步加强该领域的未来研究战略。在这些会议期间，登革热领域的前沿话题被介绍和讨论。这项申请的主要目标之一是保证来自拉丁美洲和加勒比地区的许多毕业生和初级调查人员的参与，他们在科学界的任职人数通常偏低。

 DESCRIPTION (provided by the applicant): DENVs are considered the most important emerging, human arboviruses, with worldwide distribution in the tropics, causing an estimated 50 million cases of dengue fever (DF), 750,000 cases of severe dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS), and approximately 21,000 deaths every year. According to the WHO, severe dengue is a leading cause of serious illness and death among children in some Asian and Latin American countries. In 2013, the WHO reported 2.35 million cases of dengue in the Americas alone, of which 37,687 cases were severe dengue. The field of dengue research has shown considerable expansion in the last decade, with new vaccine candidates, better understanding of disease determinants, and new developments in diagnosis, prognosis and investigational treatments. However, currently there is no specific treatment and no effective vaccines. The Pan-American Dengue Research Network Meeting (Pan-Dengue Net) is an initiative to gather researchers across the Americas every two years to discuss their recent advancements in the field, communicate this information to the scientific community in the region, foster collaborations among groups, and discuss future research strategies that will further strengthen the field. During these meetings cutting-edge topics on dengue field are presented and discussed. One of the main objectives of this application is to guarantee the participation of many graduated students and junior investigators from Latin American and Caribbean regions, which have been usually underrepresented in science The scientific meeting to be held in Belém, Brazil this year undoubtedly will make an important contribution to supporting and broadening the impact of research on dengue throughout the hemisphere.