Interrogation of streptococcal genomic epidemiology within disease endemic regions

澳大利亚北部土著人口中的A组链球菌(GAS)细菌感染率是世界上最高的之一。该项目使用比较细菌基因组学来检查澳大利亚北部相对于全球来源的天然气疾病的当前和历史爆发。这将被用来检查致病气体在偏远社区之间的传播，以及调查疾病的遗传标记和为治疗干预提供信息。

Group A streptococcal (GAS) bacterial infections within the Indigenous populations of Northern Australia are amongst the highest in the world. This project uses comparative bacterial genomics to examine current and historical outbreaks of GAS disease in Northern Australia relative to globally sourced GAS. This will be used to examine the spread of disease causing GAS between remote communities as well as investigating genetic markers of disease and informing therapeutic interventions.