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中文摘要
翻译
核心A协调实现孔蒂中心科学使命所需的资源和设施。它有四个互补的功能:1。对研究者、受训者和工作人员的行政协调包括执行NIH、大学和IRB指南、分配资源、进度报告、审查新举措、与大学和社区联络、制定政策。2.研究者、学员和工作人员之间的学术协调包括沟通、教育活动的整合、与神经科学项目的联络、合格学员的招募。康特中心将保持一个全面的外展计划,以社区,有助于传播有关精神分裂症的基础和临床神经科学研究的信息,通过在地方,区域和国家会议上发言,并以开放式的形式,邀请公众到宾夕法尼亚州。通过核心B和项目,该核心协调中心的网站,确保访问中心生成的数据、研究工具和生物材料,并促进与咨询委员会的互动。3.人力资源项目的招聘和评估(一、四、五)。标准化的程序适用于患有精神分裂症的青少年、易患精神病的人和健康的人。这包括评估医学,神经和精神状态,计算机神经认知措施和基因分型。该核心提供了对临床病史的系统评估,并介绍了在项目IV和V中捐赠大脑用于死后研究的个人,并协调数据和生物统计核心(核心B)和项目(I,IV,V)的数据传输。核心A为未来的研究和综合项目保持登记,并在中心和合作项目中提供临床神经科学培训。4.动物项目参与者的分配提供了方案的协调,与核心B一起跟踪参与者在项目II、III和IV中的流动,并与动物项目的调查者和研究人员密切合作,以确保达到科学目标。这与人类研究平行进行,保持整个中心的高度整合。
英文摘要
Core A coordinates the resources and facilities necessary for attaining the scientific mission of the Conte Center. It has four complementary functions: 1. Administrative Coordination to investigators, trainees and personnel includes implementation of NIH, University and IRB guidelines, allocation of resources, progress reports, review new initiatives, provide liaison with University and Community, establish policies. 2. Academic Coordination among investigators, trainees and personnel includes communication, integration of educational activities, liaison with neuroscience programs, recruitment of qualified trainees. The Conte Center will maintain a comprehensive outreach program to the community that contributes to dissemination of information regarding basic and clinical neuroscience research in schizophrenia through speakers in local, regional and national meetings and in an open-house format, inviting the public to Penn. With Core B and Projects, this Core coordinates the Center's website, ensure access to data, research tools and biological material generated by the Center, and facilitate interaction with the Advisory Board. 3. Recruitment and Assessment for human Projects (I, IV,V). Standardized procedures are applied to youths with schizophrenia, psychosis- prone and healthy people. This includes evaluation of medical, neurological and psychiatric status, computerized neurocognitive measures and genotyping. The Core provides systematic assessment of clinical history and presentation of individuals whose brains are donated for postmortem research in Projects IV and V and coordinates data transfer to Data and Biostatistics Core (Core B) and Projects (l,IV,V). Core A maintains a registry for future studies and integrative projects, and provide training in clinical neuroscience in the Center and collaborating programs. 4. Allocation of participants to animal projects provides coordination of the protocols, tracking with the Core B the flow of participants across Projects II, III and IV and works closely with investigators and research personnel in the animal projects to ensure that the scientific goals are met. This is done in parallel to the human studies maintaining high level of integration across the Center.
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Evolution of Psychosis in Youth: Multimodal Risk and Resilience Markers
  • 批准号:
    10401818
  • 项目类别:
  • 资助金额:
    $72.62万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
1/9: Dissecting the effects of genomic variants on nenriched for neuropsychiatric disorderseurobehavioral dimensions in CNVs
  • 批准号:
    10088064
  • 项目类别:
  • 资助金额:
    $38.78万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
Evolution of Psychosis in Youth: Multimodal Risk and Resilience Markers
  • 批准号:
    10612018
  • 项目类别:
  • 资助金额:
    $71.46万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
1/9: Dissecting the effects of genomic variants on nenriched for neuropsychiatric disorderseurobehavioral dimensions in CNVs
  • 批准号:
    10597092
  • 项目类别:
  • 资助金额:
    $74.77万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
海外基金