Sample Collection and General Screening Protocols

该项目的目的是筛选志愿者，以进行涉及研究药物管理的方案，并收集人体标本，如血液，粘膜分泌物，皮肤拭子，皮肤活检或体液，并在某些情况下进行放射成像和临床评估，以支持实验室研究并验证用于评估临床试验免疫原性结果的研究分析。这些样品和数据将供实验室研究人员用于开发针对艾滋病毒和其他传染病的疫苗和单克隆抗体，研究与传染病有关的免疫的相关性，以及用于开发和/或验证免疫分析的实验室工作。为了进行研究，有时需要获得比简单的静脉切开术安全获得的更多的血浆或单个核细胞。这些成分可以使用在NIH临床中心输血医学系（DTM）进行的单采程序安全地获得。

The purpose of this project is to screen volunteers for protocols that involve the administration of investigational agents and to collect human specimens, such as blood, mucosal secretions, skin swabs, skin biopsy, or body fluids, and in some circumstances perform radiographic imaging and clinical evaluations, to support laboratory research studies and to validate research assays used in evaluation of clinical trials immunogenicity results. These samples and data will be used by laboratory researchers in their work on the development of vaccines and monoclonal antibodies targeting HIV and other infectious diseases, to study the correlates of immunity related to infectious diseases, and in laboratory work related to the development and/or validation of immunological assays. In order to carry out research studies, it is sometimes necessary to obtain larger quantities of plasma or mononuclear cells than can be safely obtained by simple phlebotomy. These components can be safely obtained using apheresis procedures, which are performed in the NIH Clinical Center Department of Transfusion Medicine (DTM).