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中文摘要
翻译
描述(由申请人提供):本提案的目标是获得对运动和康复科学跨学科工程职业发展中心的支持,该中心由该领域的领先机构组成的财团创建,包括西北大学、芝加哥康复研究所、加州大学欧文分校、加州大学 北卡罗来纳州、凯斯西储大学、马奎特大学、斯坦福大学和特拉华大学。拟议计划的使命是培养具有工程学和其他量化背景的学者,使其成为基础、翻译和/或临床研究中成功的康复科学家。这将是同类项目中唯一一个专注于受过工程训练的调查人员的项目。私人投资机构认为,这些人已经拥有强大的量化、解决问题、编程、信号分析和机电一体化技能,他们处于独特的地位,可以在量化运动和康复科学(MRS)领域及其向康复护理的转化方面产生重大影响。拟议的职业发展计划旨在为学者提供:1)深入了解以患者为中心的康复临床问题;2)职业发展机会和指导,以扩大他们的MRS研究和培训;以及3)在翻译研究方面的指导,以增加他们工作的影响。PIS将通过使用由一名高级工程学教员和一名高级临床康复教员组成的双重导师模式来实现这些目标。此外,学者将参加休假体验,在那里他们可以在康复和工程实验室进一步加深他们的知识和研究技能。参与机构在运动行为和功能障碍的神经生物学、康复机器人、感觉-运动神经机器接口以及肌肉骨骼建模和功能障碍的研究方面有着悠久和公认的历史。从侧重于控制运动和运动障碍的基本动物和人体研究,到开发解决这些运动障碍的新型康复机器人干预措施,这些领域正在进行广泛的研究。这一系列令人印象深刻的既定研究项目不仅将为工程学者在MRS领域的发展提供肥沃的土壤,还将促进新的跨学科和机构间合作的创建,从而使新的发现结出硕果。专业人员计划在职业发展方案的第一年总共支持4名学者,并在随后的几年中支持8名学者。该计划将为每位奖学金获得者提供为期两年的资助。
英文摘要
DESCRIPTION (provided by applicant): The goal of this proposal is to attain support for a new Interdisciplinary Engineering Career Development Center in Movement and Rehabilitation Sciences created by a consortium of leading institutions in the field including Northwestern University, the Rehabilitation Institute of Chicago, University of California Irvine, University of North Carolina, Case Western Reserve University, Marquette University, Stanford University, and University of Delaware. The mission of the proposed program is to develop scholars with engineering and other quantitative backgrounds to become successful rehabilitation scientists in basic, translational and/or clinical research. This would be the only program of its kind to focus on engineering-trained investigators. The PIs believe that these individuals, who already possess strong quantitative, problem-solving, programming, signal analysis and mechatronics skills, are uniquely positioned to make a significant impact on the field of quantitative movement and rehabilitation sciences (MRS) and its translation to rehabilitative care. The proposed career development program seeks to provide scholars with: 1) In-depth understanding of rehabilitation patient-centered clinical problems; 2) Career development opportunities and mentoring to broaden their MRS research and training; and 3) Mentoring in translational research to increase the impact of their work. The PIs will accomplish these goals by using a dual mentorship model with a senior engineering faculty member and a senior clinical rehabilitation faculty member. In addition, scholars will participate in sabbatical experiences where they can further their knowledge and research skills in rehabilitation and engineering laboratories. The participating institutions have a long and recognized history in the study of the neurobiology of movement behavior and dysfunction, rehabilitation robotics, sensory-motor neural machine interfaces, and musculoskeletal modeling and dysfunction. Extensive research is being performed in these areas, across the continuum, from basic animal and human studies focused on the control of movement and movement disorders, to the development of novel rehabilitation robotics interventions that address these movement disorders. This impressive array of established research programs will not only provide a fertile ground for the development of engineering scholars in the field of MRS, but will also foster the creation of new interdisciplinary and inter-institutional collaborations that will bring new discoveries to fruition. The PIs intend to supporta total of 4 scholars in year 1 of the career development program, and 8 scholars in subsequent years. The program will provide support for a total of two years for each scholar.
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Contralesional Corticobulbospinal Structural and Functional Changes Post Stroke: Biomarkers for the upper limb flexion synergy
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