2014 Metals in Medicine Gordon Research Conference

描述（由申请人提供）：鉴于用于治疗、成像和其他应用的新型金属基药物的开发的增长，药用无机化学仍然是一个具有巨大潜力的领域。2014年“医学中的金属”戈登研究会议（GRC）将汇集来自学术界，工业界和政府的125多名博士科学家和临床医生，讨论该领域的最新发展，在轻松的大学环境中，GRC的特点。这些与会者将包括许多学生，博士后研究员和早期职业研究人员，他们的出席将通过提供会议注册和差旅费的报销来促进。2014年“医学中的金属”GRC的组织者有四个具体目标：1）说明和讨论最近批准的金属药物的成功; 2）探索重要健康相关疾病的研究机会; 3）鼓励未来几代年轻科学家参与药物无机化学领域提供的跨学科研究机会;及4）为药物无机化学研究者提供一个核心论坛，促进新的研究机会和新的合作。目标1和2将通过传统的GRC科学会议来实现，这些会议将邀请该领域的领导者，包括尽可能优秀的年轻科学家。将在2014年“医学中的金属”研讨会上讨论的技术领域包括：（a）金属络合物对非经典DNA的识别;（B）钆和金等金属在MRI和CT造影剂中的应用;（c）无机纳米颗粒在医学中的应用;（d）金属药物的药理学。目标3将通过两种方式实现。首先，从会议上展示的海报中选出的六名研究生和博士后研究员的工作将在两次口头海报会议上展出，高级研究人员及其同行将提供指导和反馈。第二，从提交的摘要中选出的三位早期职业调查员的工作将在周四晚上的“新前沿”会议上展出。目标4将通过汇集来自世界各地的学术界，工业界和政府实验室的该领域最杰出的研究人员以及大量非常有前途的年轻科学家来实现，在宽松的大学环境中，为思想的自由交流提供肥沃的土壤，以及开发新合作的多种机会。

DESCRIPTION (provided by applicant): Medicinal inorganic chemistry continues to be a field with tremendous potential given the growth in the development of new metal-based drugs for therapy, imaging, and other applications. The 2014 "Metals in Medicine" Gordon Research Conference (GRC) will bring together more than 125 PhD scientists and clinicians from academia, industry, and government to discuss the latest developments in the field in the relaxed collegial environment characteristic of a GRC. These attendees will include many students, postdoctoral fellows and early-career investigators whose attendance will be facilitated by offering reimbursements for their conference registration and travel expenses. The organizers of the 2014 "Metals in Medicine" GRC have four Specific Aims: 1) To illustrate and discuss the successes of recently approved metal-based drugs; 2) To explore research opportunities in important health-related disorders; 3) To encourage future generations of young scientists to become involved with the interdisciplinary research opportunities offered in the fiel of medicinal inorganic chemistry; and 4) To provide a nucleating forum for researchers in medicinal inorganic chemistry, facilitating new research opportunities and new collaborations. Aims 1 and 2 will be accomplished through the traditional GRC scientific sessions, which will feature leaders in the field, including outstanding younger scientists whenever possible. Examples of the technical areas that will be discussed at the 2014 "Metals in Medicine" GRC include: (a) non-canonical DNA recognition by metal complexes; (b) the use of metals such as gadolinium and gold in MRI and CT contrast agents; (c) applications of inorganic nanoparticles in medicine; and (d) the pharmacology of metal-based drugs. Aim 3 will be accomplished in two ways. First, the work of six graduate students and postdoctoral fellows, selected from among the posters presented at the conference, will be featured in two oral poster sessions where senior investigators as well as their peers will offer guidance and feedback. Second, the work of three early-career investigators, selected from the submitted abstracts, will be featured in the Thursday evening "New Frontiers" session. Aim 4 will be accomplished by bringing together the most prominent researchers in the field from academics, industry, and government labs around the world as well as a large number of extremely promising younger scientists in a relaxed collegial environment that provides fertile ground for the free exchange of ideas as well as multiple opportunities to develop new collaborations.