Effects of Training in Visuospatial Working Memory

描述(申请人提供)：前额叶皮质(PFC)是大脑的一个区域，对视觉工作记忆等认知过程至关重要。之前在前额叶皮质进行的几乎所有工作记忆研究，特别是在动物模型中，都使用了在行为任务方面接受过高度训练的受试者。人们对这种训练的影响知之甚少 前额叶皮质，以及本机工作记忆反应如何因训练范式而改变。本实验将研究视觉空间工作记忆任务完成前后前额叶皮质前部和后部的特点，以确定前额叶皮质在这些时间点的神经生理结构。类似地，实验还将调查在多刺激任务的训练之前和之后输入视觉空间刺激的工作记忆容量限制的特性。这些实验的结果将提供有关大脑中视觉工作记忆处理的信息，并将为中风等神经疾病以及注意力缺陷等条件下的工作记忆训练策略提供见解 多动症。

DESCRIPTION (provided by applicant): The prefrontal cortex (PFC) is an area of the brain essential for cognitive processes such as visual working memory. Nearly all previous working memory studies in the prefrontal cortex, especially in animal models, have used subjects that were highly trained in behavioral tasks. Very little is known about the effects of this training on the prefrontal cortex and how native working memory responses are altered due to the training paradigm. The experiments proposed will study the properties of the anterior and posterior prefrontal cortex divisions prior to and following mastery of visuospatial working memory tasks in order to determine the neurophysiological structure of the prefrontal cortex during these time points. Similarly, the experiments will also investigate the properties of the working memory capacity limit for incoming visuospatial stimuli prior to and following training in a multiple-stimulus task. The results from these experiments will provide information about the processing of visual working memory in the brain and will provide insights on working memory training strategies in neurological disorders such as stroke as well in conditions such as attention deficit hyperactivity disorder.