Sensory Transduction

描述（由申请人提供）：我们的感官为我们提供了执行生命所有基本功能所需的信息：导航世界、躲避危险、寻找食物、选择配偶和养育后代。每一种感觉模式都被调整到一组特定的刺激；这种调节设定了我们感官体验的极限。因此，了解感觉细胞如何检测和转导感觉刺激对于理解神经系统如何对环境作出反应以产生适当的行为和感知至关重要。此外，从失明到耳聋到对疼痛不敏感等疾病中感觉信号的中断对人类来说可能是毁灭性的。尽管有充分的证据表明，在将感官输入转化为神经信号方面，存在着共同的分子成分和共同的原理，但研究不同感官的研究人员很少有机会直接互动。随着新技术的不断涌现，需要及时的信息共享来极大地促进感官生物学的研究。本次会议提案的目标是聚集所有感官模式（视觉，嗅觉，味觉，触觉，温度，疼痛）的领先研究人员，并创建一个旨在激发现有和新兴研究人员以及研究生和博士后之间的新合作的事件。这次名为“感觉转导”的会议将是第68届普通生理学家协会年会，该会议长期以来一直被认为是生理学家、细胞生物学家和生物物理学家的先驱和高影响力会议。场地位于马萨诸塞州伍兹霍尔的海洋生物实验室校园，这是一个神奇的地方，为参与者提供了一个亲密的环境，并有充足的机会在正式和非正式的环境中分享科学见解。

DESCRIPTION (provided by applicant): Our senses provide us with the information that we need to perform all the essential functions of life: navigate the world, avoid danger, find food, choose mates and nurture our offspring. Each sensory modality is tuned to a specific set of stimuli; this tuning sets the limits of our sensory experience. Thus understanding how sensory cells detect and transduce sensory stimuli is critical to understanding how the nervous system responds to the environment to generate appropriate behaviors and perceptions. Moreover, disruption of sensory signaling in diseases ranging from blindness to deafness to insensitivity to pain can be devastating for humans. Despite ample evidence of shared molecular components and shared principles for transforming sensory input to neural signals across the senses, researchers investigating distinct senses rarely have opportunities to interact directly. With new technologies emerging at an ever- increasing rate, the timely sharing of information is needed to greatly accelerate research in sensory biology. The goal of this conference proposal is to assemble leading researchers across all sensory modalities (vision, smell, taste, touch, temperature, pain) and create an event designed to spark new collaborations among established and emerging investigators as well as graduate students and postdoctoral fellows. The conference, entitled "Sensory Transduction", will be the 68th Annual Symposium of the Society of General Physiologists (SGP), a conference that has long been recognized as a pioneering and high- impact meeting for physiologists, cell biologists, and biophysicists. The venue, the campus of the Marine Biological Laboratory in Woods Hole, MA, is a magical place that affords participants with an intimate environment and ample opportunities to share scientific insight in both formal and informal settings.