Investigating the Role of Exosomal Shuttle RNA in Mediating Pathogenesis of Neurodegenerative Disorders
Investigating the Role of Exosomal Shuttle RNA in Mediating Pathogenesis of Neurodegenerative Disorders
批准号:
nhmrc : 567046
负责人:
Dr Shayne Bellingham
金额:
$19.51万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2013-12-31
中文摘要
患痴呆症的风险随着年龄的增长而增加,这给澳大利亚的医疗资源带来了越来越大的负担。新的遗传信号可以在细胞之间进行交流。这一过程可能会导致与痴呆症相关的疾病的发展,如阿尔茨海默氏症和Prion病。我们希望确定细胞之间传递的可能导致痴呆症的遗传信号。这将帮助我们开发新的治疗方法,延缓或最终预防阿尔茨海默氏症和普里恩病。
英文摘要
The risk for dementia increases with age and is placing a growing burden upon Australian medical resources. Novel genetic signals can be communicated between cells. This process may contribute to the development of dementia related disorders, such as Alzheimer's and Prion diseases. We hope to identify the genetic signals communicated between cells that may contribute to dementia. This will help us develop novel treatments that delay the onset or ultimately prevent Alzheimer's and Prion disease.
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会议论文
Identification and Characterisation of Genes involved in the Copper Regulation of the Human Alzheimer's Disease Amyloid-Beta Precursor Protein (APP) Gene
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批准号:DI0560757
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项目类别:Discovery Indigenous Researchers Development
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资助金额:$11.45万
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财政年份:2005
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负责人:Dr Shayne Bellingham
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依托单位:
海外基金