Acquisition of a Siemens Console and Gradients for a 7T MRI/MRS System

项目摘要 该提案旨在通过以下方式将仅头部的7 T Agilent/Varian MRS扫描仪转换为7 T Siemens扫描仪： 更换控制台和所有的射频和梯度硬件。这将产生最先进的MRS和MRI 系统，以满足多达60个主要研究人员的研究需求，目前在耶鲁大学磁扫描 共振研究中心（MRRC）。升级解决了几个问题。首先，安捷伦宣布， 不再生产7 T磁体，所以如果耶鲁要有7 T MRI，升级现有系统是唯一的选择。 前进的道路。其次，由于安捷伦的这一声明，对当前系统的支持将很快 不再可用，并且在没有这样的升级的情况下，该昂贵/重要的资源可能丢失。第三我们 耶鲁大学对结构和功能成像能力有强烈的需求， 时间分辨率，并通过升级这种磁铁，我们可以提供这样的能力，以一个大的研究 在耶鲁内外的社区。此外，我们在这两个领域都有一些培训计划。 工程和神经科学将受益于这种升级的高视场成像仪。我们有 技术专长，与西门子的研究关系，几个非常强大的研究项目， 和用户需求，来证明这一投资的合理性。耶鲁大学已经投入了大量的资源， MRRC，在这种情况下，将提供50%的费用，这表明了重要性， 大学提供这种资源。这将是美国唯一的头部MRI 68 cm孔7 T Siemens系统。 世界上还有另外两个-一个在瑞士的Luasanne，另一个在加拿大的Waterloo， 这将是一个独特的资源。

Project Summary This proposal is aimed at converting a head-only 7T Agilent/Varian MRS scanner to a 7T Siemens scanner by replacing the console and all the RF, and gradient hardware. This will yield a state-of-the-art MRS and MRI system to serve the research needs of up to 60 principal investigators that currently scan in the Yale Magnetic Resonance Research Center (MRRC). The upgrade solves several problems. First Agilent has announced it is no longer going to make 7T magnets so if Yale is to have a 7T MRI, upgrading this existing system is the only path forward. Second because of this announcement from Agilent, support for the current system will shortly no longer be available and this expensive/important resource may be lost without such an upgrade. Third we have a strong demand at Yale for both structural and functional imaging capabilities at very high spatial and temporal resolution and by upgrading this magnet we can provide such capabilities to a large research community both within and outside of Yale. Furthermore we have several training programs in both engineering and neuroscience that would benefit from access to this upgraded high field imager. We have the technical expertise, the research relationship with Siemens, several exceptionally strong research programs, and the user needs, to justify this investment. Yale has invested a considerable amount of resources in the MRRC and in this case would provide 50% of the cost of this upgrade demonstrating the importance the university puts on this resource. This would be the only head-MRI 68cm bore 7T Siemens system in the USA. Two others exist in the world - one in Luasanne, Switzerland and the other in Waterloo, Canada and thus this would be a unique resource.