42nd Annual Meeting of the American Aging Association

申请者描述(申请人提供)：本申请申请资助将于5月31日至6月3日在马里兰州巴尔的摩市内港喜来登酒店举行的2013年美国老龄协会第42届年会(AGE)。由于过去几年来，对抗老龄化有害方面的有希望的战略大幅增加，会议的主题将是“老龄化：预防、逆转和减缓”。拉多拉·汤普森博士、AGE计划委员会(Thompson、Brown-Borg、Forster博士)、AGE执行委员会(Bickford、Harman、Ingram、Buffenstein博士以及Thompson、Brown-Borg和Forster博士)和会议主席组织了这项科学计划。我们在这里的目的是提供资金，支持受邀的演讲者和初级科学家(博士后研究员、研究生或新的初级教员)，他们将从会议中受益并为会议做出贡献。我们邀请的演讲者在衰老的分子和细胞生物学、衰老生理学、衰老遗传学、实验技术开发和医疗保健问题方面的研究在国际上是公认的。众所周知，这些演讲者是他们的科学的强有力的传播者，他们激发并参与活跃的讨论。近年来，大量的遗传、药理、 饮食干预和基于运动的干预已被描述为在从单细胞生物体到人类的各种系统中延缓衰老。因此，选择这些主题背后的理由是，模型系统调查干预措施的结果显著收敛。主题包括：长寿和健康跨度：从苍蝇到人类的教训；萨科普尼症：预防、逆转和减缓的战略；骨量减少：预防、逆转和减缓的战略；减缓衰老的步伐：模仿学的作用；饮食干预在预防、逆转和减缓生物衰老过程中的影响；从长凳到床边的医疗保健；预防生物衰老和疾病的机制；以及研究老龄化和健康跨度的新兴技术。会议的目标包括：利用从线虫到人类的实验模型，召集一批领先的思想家，讨论从线虫到人类的生物衰老过程，以考虑重要的概念范式和潜在的干预措施；召集基础科学家、临床科学家和其他对预防、逆转和/或减缓衰老感兴趣的受众，以强调综合和转化性的研究结果，以此作为开发未来治疗选择的新途径的手段；创建一个论坛，自由交流关于‘预防、逆转和减缓’生物衰老过程的主题，使用几种形式鼓励思想交流；支持知名科学家、初级独立调查人员、研究生和博士后实习生；评估会议在实现其既定目标方面的有效性。我预计，传统上以合作和合作为特征的这次会议将为新疗法的智力开发和讨论提供完美的环境。

DESCRIPTION (provided by applicant): This application requests funds to support the 2013 American Aging Association 42nd Annual Meeting (AGE) to be held at the Sheraton Hotel, Inner Harbor in Baltimore, MD on May 31-June 3rd. Because promising strategies to combat the detrimental aspects of aging have increased substantially over the past years, the theme of the meeting will be "Aging: Prevention, Reversal and Slowing". Dr. LaDora Thompson, AGE Program Committee (Drs. Thompson, Brown-Borg, Forster), AGE Executive Board (Drs. Bickford, Harman, Ingram, Buffenstein, along with Thompson, Brown-Borg, and Forster), and Session Chairs organize the scientific program. Our aim here is to provide funds to support invited speakers and junior scientists (postdoctoral fellows, graduate students, or new, junior faculty) who would benefit from and contribute to the conference. The speakers we invited are internationally recognized for their research on the molecular and cellular biology of aging, physiology of aging, genetics of aging, experimental technology development, and healthcare issues. These speakers are known to be strong communicators of their science, who stimulate, and participate in, lively discussion. In recent years, a large number of genetic, pharmacological, dietary interventions and exercise-based interventions have been described that slow- down aging in various systems ranging from unicellular organisms to humans. Therefore, the rationale behind the choice of these topics is the remarkable convergence of the results from the model systems to investigate interventions. Topics include- Longevity and Health span: Lessons From Flies to Humans; Sarcopenia: Strategies for Preventing, Reversing, and Slowing; Osteopenia: Strategies for Preventing, Reversing, and Slowing; Slow the pace of aging: Role of Mimetics; Impact of Dietary Interventions in Preventing, Reversing, and Slowing Biological Aging Processes; Bench to Bedside to Healthcare; Mechanisms to Protect Against Biological Aging and Disease; and Emerging Technologies for Studying Aging and Health span. The goals of the conference include: To assemble a team of leading thinkers on the subject of 'preventing, reversing and slowing' biological aging processes, using experimental models from C. elegans to humans, to consider important conceptual paradigms and potential interventions; To assemble an audience of basic scientists, clinical scientists and others with an interest in preventing, reversing, and/or slowing aging in order to emphasize integrative and translational research findings as a means to develop novel future avenues for therapeutic options; To create a forum for free exchange of ideas on the subject of 'preventing, reversing and slowing' biological aging processes, using several formats to encourage exchange of ideas; To support established scientists, junior independent investigators, graduate students, and post-doctoral trainees; To evaluate the effectiveness of the conference in achieving its' stated objectives. It i anticipated that the collegial and cooperative atmosphere that has traditionally characterized this meeting will provide the perfect setting for the intellectual development and discussion of novel therapeutics.