Post-Doctoral Research Training in Genetic Epidemiology

描述（由申请人提供）：这一修订后的博士后研究培训支持更新申请的主要目标是产生尖端的独立科学家和遗传流行病学未来的研究领导者。我们建议在多学科环境中进行这项工作，重点是心血管疾病（CVD）和CVD危险因素以及与心脏，肺和血液疾病相关的其他复杂特征的实质性应用方向。我们已经与我们机构的心脏病学奖学金计划做出了合作安排，这样我们就可以积极招募医学博士（和医学博士/博士）。我们相信华盛顿大学的研究环境对于开展心血管遗传流行病学研究来说是杰出的。这个年轻的计划的基石是强调在经验丰富的导师的监督下对每个学员进行密集和持续的个性化培训。事实上，强调个性化培训是其标志之一。它的核心是由项目总监、受训者的导师和受训者为每个受训者开发的个性化培训途径（ITP）。每个学员的ITP将反映他/她的教育背景，以前的研究经验（如果有的话），学员的特殊研究兴趣，并将解决课程需求以及他/她需要的研究经验类型。项目主任和参与导师倡导的研究和培训理念的重点是清楚地了解调查CVD和相关复杂特征的生理和病理生理过程所需的遗传流行病学的概念，原则和方法。我们正在申请资金，以继续支持每年4个名额（一半的名额用于MD和MD/PhD）。我们的建议通过混合和整合精心选择的教学培训，更加强调直接动手研究和赠款写作经验，从而迎接挑战。该培训计划的一大优势是，整个DBBS的庞大的既定资源和丰富的跨学科培训环境，以及我们的GEMS和MSIBS硕士学位培训计划的资源和环境，可供该计划的所有博士后学员使用。拟议的博士后研究培训计划旨在培养未来的遗传流行病学家，以满足当前市场对心血管和其他生物医学研究的需求。华盛顿大学的研究培训环境是杰出的，它也有一个独立的研究生事务办公室来照顾博士后学员和他们的特殊需要，并作为他们的倡导者。

DESCRIPTION (provided by applicant): The primary objective of this revised renewal application for post-doctoral research training support is to produce cutting edge independent scientists and future research leaders in genetic epidemiology. We are proposing to do this in a multidisciplinary setting with emphasis on substantive applied orientation in cardiovascular disease (CVD) and CVD risk factors and other complex traits related to heart, lung, and blood disorders. We have made partnership arrangements with cardiology fellowship programs at our institution so that we can actively recruit MDs (and MD/PhDs) in addition to PhDs. We believe that the research environment at Washington University is outstanding for carrying out research in cardiovascular genetic epidemiology. The cornerstone of this young program is its emphasis on intense and sustained individualized training of each trainee under the supervision of an experienced preceptor. Indeed, emphasis on individualized training is one of its hallmarks. Its centerpiece is an Individualized Training Pathway (ITP) developed for each trainee by the Program Director, the trainee's preceptor(s), and the trainee. An individual trainee's ITP will reflect his/her educational background, the previous research experience if any, the particular research interests of the trainee, and will address the curriculum needs as well as the type of research experience he/she needs. The focus of the research and training philosophy advocated by the Program Director and the participating preceptors is a clear understanding of the concepts, principles, and methods of genetic epidemiology necessary for investigating the physiological and pathophysiological processes that underlie CVD and related complex traits. We are requesting funds for continuing to support 4 slots each year (with half the slots devoted to MDs and MD/PhDs). Our proposal rises to the challenge by blending and integrating carefully chosen didactic training with greater emphasis on a direct hands-on research and grant writing experience. One of the great strengths of this training program is that the vast established resources and rich interdisciplinary training environment of the entire DBBS, as well as those of our GEMS and MSIBS masters degree training programs are available to all post-doctoral trainees in this program. The proposed post-doctoral research training program aspires to produce future genetic epidemiologists in much demand in the current market place for pursuing cardiovascular and other biomedical research. The research training environment at Washington University is outstanding, which also has a separate Office of Post Graduate Affairs to look after postdoctoral trainees and their special needs and serve as their advocate.