PRIDE COORDINATION CENTER

 描述（由申请人提供）：摘要背景：一些种族和民族群体特别容易患某些心、肺、血和睡眠（HLBS）疾病。尽管发病率和死亡率总体上有了显著改善，但这些差距一直存在。由于预计到2043年美国人口的多样性将增加，现在就有紧迫感来解决这些差异。NIH致力于招募和留住更多样化的员工队伍，这些员工有可能贡献新的想法和创新的解决方案，以帮助减少这些差异。目的：为响应RFA-HL-14-022，这是一项竞争性更新申请，作为增加从事健康相关研究的个人多样性计划（PRIDE）的协调核心（CC）。骄傲包括多达8个暑期研究所（SI）研究教育培训计划，其总体目标是为代表性不足的群体成员的初级生物医学研究人员提供研究经验，技能发展和指导。CC将通过以下目标促进SI计划之间的教育和评估活动的协调：1）开发和协调外展工作，以招募学员和导师; 2）通过规划和协调所有8个SI计划的教师，工作人员，导师和学员参加的年度会议，促进网络联系; 3）促进SI计划，学员，导师和NHLBI之间的沟通;（4）制定和实施评价计划。评估计划将（一）评估过程和结果，（二）收集和跟踪跨时间的结果数据，以便评估PRIDE计划对增加多样性的影响，以及（三）将这些结果与国家队列进行基准测试。意义与创新：由于此应用程序是一个竞争性的更新，因此实现这些目标所需的大部分基础设施和组织已经成熟并可操作。然而，我们认识到，随着有新需求的新项目加入PRIDE，需要做出改变。我们准备根据需要对我们的协议进行及时和有效的修改。此外，这类研究的一个关键障碍是， 以及这些项目在多大程度上取得了成功，主要是因为很难找到相关的比较组。我们的申请专门解决这个问题，作为我们最终具体目标的第三部分。我们将使用1993-2000年超过100，000名医学院新生的全国队列的结果数据作为这种比较的基准。方法学：该项目是围绕我们的基于网络的基础设施，允许公众或安全访问程序信息，包括我们的在线数据输入系统。总结：我们的团队拥有专业知识和经验，可以继续作为PRIDE的协调核心，并评估RFA和本提案中概述的成功指标。此外，我们具有独特的优势，可以通过将我们的结果与我们现有的国家数据库进行比较来评估该计划的影响，并期待跟踪这些积极主动的调查人员的职业发展，因为他们带领我们走向未来。

 DESCRIPTION (provided by applicant): ABSTRACT Background: Some racial and ethnic groups are particularly susceptible to certain Heart, Lung, Blood and Sleep (HLBS) disorders. These disparities have persisted over time, even in the face of notable improvements in morbidity and mortality rates overall. Since the diversity of the US population is projected to increase by 2043, there is a sense of urgency to address these disparities now. The NIH is committed to recruiting and retaining a more diverse workforce with the potential to contribute new ideas and innovative solutions to help reduce these disparities. Objectives: In response to RFA-HL-14-022, this is a competing renewal application to serve as the Coordination Core (CC) for the Programs to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE). The PRIDE consists of up to 8 Summer Institute (SI) research education training programs with the general goal of providing research experiences, skills development and mentoring for junior level biomedical researchers who are members of underrepresented groups. The CC will facilitate the coordination of education and evaluation activities among the SI programs via the following Aims: 1) Develop and coordinate outreach efforts to recruit trainees and mentors; 2) Foster networking by planning and coordinating annual meetings to be attended by faculty, staff, mentors and trainees from all 8 SI programs; 3) Facilitate communications across the SI programs, trainees, mentors and NHLBI; and 4) Develop and implement an evaluations plan. The evaluation plan will (i) assess processes and outcomes, (ii) collect and track outcomes data across time that allows for an assessment of the impact of the PRIDE programs on increasing diversity and (iii) benchmark these outcomes against a national cohort. Significance and Innovation: Since this application is a competing renewal, much of the infrastructure and organization needed to address these aims is already mature and operational. However, we are cognizant that changes will be required as new programs with new needs join the PRIDE. We are prepared to make timely and efficient changes in our protocols as needed. In addition, a critical barrier in this type of research is in knowing whether and to what extent the programs have been successful, primarily because relevant comparison groups are difficult to find. Our application specifically addresses this issue as the third part o our final Specific Aim. We will use outcomes data about our national cohort of over 100,000 medical school matriculants from 1993-2000 as a benchmark for this comparison. Methodology: This project is built around our web-based infrastructure which allows Public or Secure access to program information, including our on-line data entry system. Summary: Our team has the expertise and experience to continue as the coordination core for the PRIDE and evaluate those indicators of success outlined in the RFA and this proposal. Further, we are uniquely positioned to assess the impact of this program by benchmarking our results against those of our existing national database, and look forward to tracking the career development of these bright motivated investigators as they lead us to the future.