Outreach Core

三分之一的美国居民，超过1亿人，是少数民族（1）。其中，超过3900万，占美国总人口的13%，是外国出生的（2）。纽约市（NYC）长期以来一直是移民的磁石，拥有300万外国出生的人，其中150万人是有限的英语熟练（LEP）（3）。这一庞大而多样化的人群在癌症发病率、诊断、治疗和结局方面存在显著差异（4-21）。 这些差异是由健康信息和系统访问障碍（19，22，23），并通过一个不充分的证据基础，这源于在研究和计划实施（24，25）的代表性不足。这些因素限制了在实验室、患者、社区和政策层面（26）之间双向转换发现，以改善结果。 在过去的4年里，PCOP已经建立了社区参与癌症差异工作的基础，该工作始于U 54的合作伙伴社区外展计划（PCOP），由纽约城市学院（CCNY）的Tiffany弗洛伊德博士和纪念斯隆凯特琳癌症中心（MSKCC）的卡罗尔布朗博士领导。PCOP开展了开创性的社区参与外展和研究，并解决了纽约市医疗服务不足的大型社区在癌症结果和护理质量方面的差距，包括CCNY所在的哈莱姆社区;大型移民社区;以及艾滋病毒感染者。通过伙伴关系和示范项目的传播，PCOP还在美国各地扩大了其推广和研究活动，是NCI和美国癌症协会几个委员会的重要成员，致力于将不同人群纳入研究。我们是NCI第5区BMaP/GMaP网络的组成部分，并正在与癌症差异研究网络合作，在Electra Paskett和Tim Rebbeck博士的指导下，为医学上服务不足的癌症风险队列开发应用程序。如果该队列得到资助，新的PCOE将在招募服务不足的社区成员加入该队列方面发挥关键作用。 为了解决U 54日益增长的社区参与性（CBPR）和翻译外展和外展相关研究重点，MSKCC招募了Jennifer Leng博士到MSKCC移民健康和癌症差异（IHCD）服务。由Francesca Gany博士领导的IHCD成立于2011年，旨在领导MSKCC在多个领域扩大U 54外展的努力，并为研究人员和社区提供核心的社区参与式研究（CBPR）工具。这项工作导致了新的命名，PCOE（合作社区拓展-研究-教育）核心，以前称为PCOP。 因此，该方案涉及一系列广泛的优先领域，通过国际人道主义合作研究所的外联/与外联有关的研究活动和通过该方案在若干领域已经完成了大量的初步工作。此外，IHCD还为MSKCC和U 54带来了大量基于社区的资源，网络和合作伙伴。冷博士将她在社区参与式研究方面的广泛背景带到了U 54。她加入博士卡罗尔布朗，MSKCC多样性计划主任，作为MSKCC PCOE Pis。克莉丝汀谢弗博士被招募加入CCNY心理学系的蒂芙尼弗洛伊德博士，作为CCNY PCORE Pis。克莉丝汀谢弗博士是CCNY索菲戴维斯生物医学教育学院社区卫生和社会医学副教授。她在服务不足的社区领导研究，以检查与烟草相关的决策相关的神经生物学和神经经济学因素，为癌症相关的风险行为开发新的治疗目标。这些PI共同带来了社区参与的外展，教育和服务，CBPR，降低癌症风险和癌症健康服务研究的显著优势。 PCOE将把CCNY和MSKCC的社区，学生和研究人员聚集在一起，建立一个强大的社区-学术伙伴关系，并为社区参与的外展和转化研究建立基础设施。

One in three U.S. residents, over 100 million people, are minorities (1). Of these, over 39 million, 13% of the entire U.S. population, are foreign-born (2). New York City (NYC), a longstanding magnet for immigrants, is home to 3 million foreign-born, 1.5 million of whom are limited English proficient (LEP) (3). This large and diverse population faces significant disparities in cancer incidence, diagnosis, treatment, and outcomes (4-21). These disparities are fueled by health information and systems access barriers (19, 22, 23), and by an inadequate evidence-base, which stems from insufficient representation in research and program implementation (24, 25). These factors limit the bi-directional translation of discoveries between bench, patient, community, and policy levels (26) for improved outcomes. Over the past 4 years, PCOP has built a foundation of community-engaged cancer disparities work begun in the U54's Partnership Community Outreach Program (PCOP), led by Dr. Tiffany Floyd of City College of New York (CCNY) and Dr. Carol Brown of Memorial Sloan Kettering Cancer Center (MSKCC). PCOP has implemented trailblazing community-engaged outreach and research, and addressed gaps in cancer outcomes and quality of care for large medically underserved communities throughout NYC, including the Harlem community in which CCNY is embedded; large immigrant communities; and underserved populations living with HIV. Through partnerships and model program dissemination, PCOP has also extended its outreach and research activities across the U.S., and is a vital member of several NCI and American Cancer Society Committees addressing the inclusion of diverse populations in research. We are an integral part of the NCI Region 5 BMaP/GMaP Network, and are working with the Cancer Disparities Research Network, under the direction of Drs. Electra Paskett and Tim Rebbeck, on the development of an application for a medically underserved cancer risk cohort on cancer risk. If the cohort is funded, the new PCORE will have a key role in recruiting underserved community members into this cohort. To address the growing community based participatory (CBPR) and translational outreach and outreach related research focus of the U54, MSKCC recruited Dr. Jennifer Leng to the MSKCC Immigrant Health and Cancer Disparities (IHCD) Service. IHCD, led by Dr. Francesca Gany, was established in 2011 to lead MSKCC's effort in growing the U54 outreach in multiple areas, and to equip researchers and the community with core community based participatory research (CBPR) tools. This work led to the new nomenclature, PCORE (Partnership Community Outreach-Research-Education) core, for what was formerly known as PCOP. PCORE thus addresses a broad range of priority areas, with substantial preliminary work already completed in several areas through IHCD's outreach/outreach-related research activities and through PCOP. IHCD additionally has brought a vast portfolio of community-based resources, networks, and partners to MSKCC and the U54. Dr. Leng brings her extensive background in community based participatory research to the U54. She joins Dr. Carol Brown, Director of MSKCC Diversity Programs, as the MSKCC PCORE Pis. Dr. Christine Sheffer was recruited to join Dr. Tiffany Floyd of the CCNY Department of Psychology, as the CCNY PCORE Pis. Dr. Christine Sheffer is an associate medical professor in community health and social medicine in the Sophie Davis School of Biomedical Education at CCNY. She leads research in underserved communities to examine neurobiological and neuroeconomic factors associated with tobacco-related decision-making, to develop new therapeutic targets for cancer-related risk behaviors. Together these Pis bring significant strength in community-engaged outreach, education, and service, in CBPR, in cancer risk reduction, and in cancer health services research. PCORE will bring together the community, students, and researchers at CCNY and MSKCC into a robust community-academic partnership and build an infrastructure for community-engaged outreach and translational research.