Techniplast Sealsafe Plus Mouse Rack System (LAMb)

 描述(由申请人提供)： 为了维持动物群体的健康，为动物提供理想环境的畜牧业原则是必不可少的。与联邦规定的做法一致，所要求的设备将最大限度地提高动物的舒适性和健康，最大限度地减少笼子中的水分和氨含量，并提供有效的屏障，防止可能的病原体。所要求的个体通风笼养为动物提供了理想的微环境。如果这一请求获得批准，我们可以将我们所有的老鼠安置在通风机架上，但我们BSL-2套房中无法容纳通风机架的老鼠除外。这些架子不仅将加强动物的饲养，还将使我们能够扩大我们的住房能力 13%，这对于跟上我们动物项目的增长是必不可少的(目前我们饲养了大约18,000只老鼠。增加通风架子的数量将增强我们确保动物福利的能力，并提供更大的灵活性，以应对调查人员不断变化的需求。由于通风笼子比标准架子容纳了更多的动物，这满足了我们不断扩大的动物研究计划对动物使用的日益增长的需求。把啮齿动物安置在像SealSafe Plus这样的通风架子里，可以保护它们免受感染剂的侵袭，保护动物使用者免受过敏原的影响，并需要向笼子里吹进大量的空气，以提供最佳的微环境，从而保持低浓度的氨、二氧化碳和稳定的氧气浓度。

 DESCRIPTION (provided by applicant): In order to maintain the health of the animal colony, principles of animal husbandry that provide an ideal environment for the animals is essential. Consistent with federal mandated practices, the requested equipment will maximize the comfort and health of the animals, minimize moisture and ammonia levels in the cages, and provide an effective barrier from possible pathogens. The requested individual ventilated caging provides an ideal microenvironment for the animal. If this request is awarded, we can house all our mice in ventilated racks, except for mice housed in our BSL-2 suite that cannot accommodate a ventilated rack. Not only will these racks enhance the husbandry of the animals, it will also allow us to expand our housing capacity by 13%, which is essential to keep up with the growth of our animal program (currently we house approximately 18,000 mice. Expanding the number of ventilated racks will enhance our abilities to ensure the welfare of the animals, as well as, provide increased flexibility to respond to the changing needs of the investigators. As the ventilated cages house more animals than standard racks, which accommodates the growing animal usage needs of our expanding animal research program. Housing rodents in ventilated racks like Sealsafe Plus will protect them from infective agents and protect the animal users from allergens and requires a high volume of air to be blown into the cages so as to provide the optimal micro-environment, thus aiming to maintain a low concentration of ammonia, carbon dioxide and a stable concentration of oxygen.