Developmental Research Projects Program (DRPP)

项目摘要 发展研究项目计划（DRPP）的总体目标是支持职业生涯 在PR-INBRE牵头机构和网络机构培养有前途的早期研究人员。DRPP是 通过提供指导和财政支持来加强研究， 网络的能力。我们将使用在当前期间建立的基础设施和协议 周期：宣传DRPP的资助和指导机会，严格的同行评审程序，以及 涉及INBRE行政核心、指导委员会、外部 咨询委员会（EAC）和NIH计划办公室。DRPP将确定有前途的研究者， 他们的职业生涯和博士后同事的早期阶段，并为他们提供不仅是经济支持，但 个性化的指导和一个有凝聚力的研究基础设施，通过以下具体目标。一是 增加和发展公关人才库，结构化的指导计划和相关的发展 将实施活动，重点是实现个人发展计划（IDP）， 加强语法和写作技巧。第二，扭转联邦资源普遍下降的趋势， 生物医学研究，我们将提供资金的有价值的研究，建议使用循证医学为基础的 研究结果，以改善人类健康，并填补我们目前的知识基础在以下专题领域的关键差距： 神经科学/行为，分子医学/癌症，药物发现/开发和生物信息学。第三、 PR-INBRE的研究基础设施将得到小型仪器的有限奖励的支持， 教学和研究的需要。这一目标还将授予INBRE合作迷你奖 研究人员将增加INBRE核心设施在PR的“OMICS”和大数据类型研究中的使用， INBRE集中研究仪器核心（CRI）和生物信息学资源核心（BiRC）。作为 我们目前在获得R型资金和DRPP同行评审出版物方面取得的成功表明了这一点 研究人员，结果将通过内部和外部评估和跟踪成功的赠款来衡量 和稿件提交和实现独立的资金。因此，这些目标旨在 鼓励INBRE和COBRE机构之间的跨学科研究，增加 授予DRPP调查人员的外部资金，提高了PR-INBRE调查人员的质量， 出版物，并指导合格的研究人员通过R15和R21奖项获得独立资金。 这些战略预计最终将导致一个训练有素的干部代表性不足的科学家 促进健康益处和增加生物医学科学的多样性。因此，DRPP预计， 组织，建立和发展一个激励，高效和协作的研究计划，将 加强我们在国家和国际一级竞争研究突出地位的能力。

Project Summary The overall goal of the Developmental Research Project Program (DRPP) is to support the career development of promising early stage investigators at PR-INBRE lead and network institutions. The DRPP is central to the success of the PR-INBRE by providing mentoring and financial support to enhance the research capacity of the network. We will use the infrastructure and protocols that were established during the current cycle for: publicizing the DRPP funding and mentoring opportunities, the rigorous peer-review procedure, and the funding decision process involving the INBRE Administrative Core, Steering Committee (SC), External Advisory Committee (EAC), and the NIH Program Office. The DRPP will identify promising investigators in the early stages of their careers and postdoctoral associates, and provide them with not just financial support, but individualized mentoring and a cohesive research infrastructure by the following Specific Aims. First, to increase and develop the talent pool in PR, a structured mentoring program and related developmental activities will be implemented, with an emphasis on fulfillment of Individual Developmental Plans (IDP) and reinforcing grantsmanship and writing skills. Second, to reverse the general decline in federal resources for biomedical research, we will provide funds for meritorious research that proposes to use evidence-based findings to improve human health and fill critical gaps in our current knowledge base in the thematic areas of Neuroscience/Behavior, Molecular Medicine/Cancer, Drug Discovery/Development, and Bioinformatics. Third, the research infrastructure of the PR-INBRE will be buttressed by limited awards for small instruments for teaching and research needs of the PUIs. This Aim will also grant collaborative mini awards to INBRE investigators to augment the use of INBRE Core facilities for “OMICS” and big-data type studies at the PR- INBRE Centralized Research Instrumentation Core (CRI) and the Bioinformatics Resources Core (BiRC). As shown by our current success in obtaining R-type funding and peer-reviewed publications by the DRPP investigators, outcomes will be measured by internal and external Evaluation and Tracking of successful grant and manuscript submission and achievement of independent funding. Therefore, these Aims are designed to encourage interdisciplinary research among the INBRE and COBRE institutions, increase the number of extramural funds awarded to the DRPP investigators, augment the quality of PR-INBRE investigators’ publications, and mentor qualified investigators to obtain independent funding through R15 and R21 awards. These strategies are expected to result in a highly trained cadre of underrepresented scientists ultimately contributing to health benefits and increased diversity in the biomedical sciences. Thus, the DRPP expects to organize, establish, and develop a stimulating, highly productive, and collaborative research program that will strengthen our capabilities to compete for research prominence at the national and international level.