2015 Cartilage Biology & Pathology Gordon Research Conference and Gordon Research Seminar

 描述（由申请人提供）：这是一个请求，以支持2015年戈登研究会议（GRC）和相关研讨会（GRS）的软骨生物学和病理学，将在加尔维斯顿，得克萨斯州举行。全球研讨会将是一系列非常成功的两年期会议中的第七次，在此之前将首次举行全球研讨会，这是一次专门为受训人员举办的会前会议。骨关节炎生物学和病理学GRC的成功归功于三个主要原则。首先，它是唯一一个汇集了临床医生，科学家，基础科学研究人员和生物医学工程师的会议，涵盖了软骨病理学和软骨研究学科的整个范围。第二，体现了GRC的传统，会议强调前瞻性思维，未发表的前沿发现和最先进的技术，将正式演讲与海报会议和非正式讨论交替进行，并将出席人数限制在200人以内，这是一个促进学院互动和建立富有成效的合作的论坛。第三，它对所有职业阶段的研究人员开放，并鼓励有抱负的年轻和高级研究人员之间的指导，网络和合作。2015年将增加一个全球报告系统，进一步强调最后一项原则。软骨生物学和病理学的GRS/GRC不仅是因为软骨是从发育到发育的关键骨骼组织， 软骨畸形和退行性疾病影响了大部分人的寿命和生活质量，并且在很大程度上仍然无法治愈。因此，当务之急是开展研究，更好地了解这些疾病的原因和进展，并找到扭转甚至根除这些疾病的战略。为了帮助改变软骨疾病的临床现实，GRS将突出了解软骨疾病的最新进展和挑战，GRC的首要主题是“共同努力，在科学和技术的前沿，以消除软骨疾病”。杰出的科学家和有前途的年轻研究人员将根据这一主题刺激观众，并将在科学会议上直接讨论最新进展和剩余的挑战，以了解软骨生物学，疾病类型和翻译方法的各个方面。我们希望这些2015年GRC/GRS对软骨生物学和病理学授权跨学科的研究人员取得里程碑式的进展，以改善人类的健康与所有类型的软骨疾病，从而实现美国国立卫生研究院的使命。

 DESCRIPTION (provided by applicant): This is a request to support the 2015 Gordon Research Conference (GRC) and associated Seminar (GRS) on Cartilage Biology and Pathology that will be held in Galveston, Texas. The GRC will be the seventh in a series of highly successful biennial conferences, and it will be preceded for the first time by a GRS, a pre-meeting exclusively dedicated to and organized by trainees. The GRC on Cartilage Biology and Pathology owes its success to three major principles. First, it is the only conference that brings together clinicians-scientists, basic- science researchers and biomedical engineers, and covers the whole spectrum of cartilage pathologies and cartilage research disciplines. Second and exemplifying the GRC tradition, the conference emphasizes forward thinking, unpublished cutting-edge findings, and state-of-the-art technologies, alternates formal presentations with poster sessions and informal discussions, and limits attendance to 200 participants, a forum that promotes collegial interactions and establishment of productive collaborations. Third, it is open to researchers at all career stages and encourages mentoring, networking, and collaborations among aspirant, young and senior investigators. This last principle will be further emphasized in 2015 with the addition of a GRS. The GRS/GRC on Cartilage Biology and Pathology are justified not merely by the fact that cartilage is a pivotal skeletal tissue from development on to adulthood, but even more so by the fact that cartilage malformation and degeneration diseases affect the lifespan and quality of life of a large proportion of humans and remain largely incurable. Research to better understand the causes and progression of these diseases and to find strategies to reverse and even eradicate them is thus a top priority. In order to help change the clinical reality of cartilage diseases, the GRS will highlight recent advances and challenges in understanding cartilage diseases and the overarching theme of the GRC is entitled "working together at the frontiers of Science and technologies to eradicate cartilage diseases". Eminent scientists and promising young investigators will stimulate the audience according to this theme and will present in scientific sessions directly addressing the newest advances and remaining challenges towards understanding the various aspects of cartilage biology, disease types, and translational approaches. We expect these 2015 GRC/GRS on Cartilage Biology and Pathology to empower researchers across disciplines to make milestone progress towards improving the health of humans with all types of cartilage diseases and thus towards fulfilling the missions of the National Institutes of Health.