Developmental Research Program

相对于其不断增长的发病率，对甲状腺癌的翻译研究还不发达，对 公共卫生和可利用的科学机会。发展性研究 该计划将在促进对这种疾病的研究方面发挥重要作用。我们将使用DRP资金 辅以机构资金的坚定承诺，通过新的和 成熟的研究人员，这对甲状腺癌诊断和治疗的新想法的产生至关重要 治疗。我们的目标是建立快速筹资机制，加快重要的新方向 朝着我们孢子的翻译研究目标迈进。我们确定了可信的投资组合 前景看好的发展研究项目，一旦计划完成，它们将争夺支持 已经成立了。我们将向临床和基础部门征求有翻译潜力的甲状腺试点项目建议书 更大的MSKCC社区内的调查人员，包括洛克菲勒大学，纽约长老会 他来自康奈尔大学威尔医学院以及阿尔伯特·爱因斯坦医学院。 然后，我们将在执行人员进行严格的同行审查后，选择最有希望的新项目进行支持 委员会、内部咨询委员会和患者权益倡导者。外部评审员的意见 将根据需要征求意见。试点项目将获得为期1年的资金，但调查人员可以申请额外的 第二年通过同样的竞争过程提供资金。每年，内部咨询委员会 执行委员会成员开会审查每个研究项目、核心和发展试点 项目。委员会成员将被要求评估是否有任何发展项目取得进展 充分和显示出足够的翻译潜力，使一个完整的研究项目黯然失色。 然后，委员会成员将投票并决定是否应该推进任何发展项目 到完全的研究状态。如果是这样的话，将对预算进行适当调整，并将其送至 主任医师和滑雪场总监，在与NCI的TRP协商后。

Translational research into thyroid cancer is underdeveloped relative to its growing incidence, impact on public health and to the scientific opportunities that could be exploited. The Developmental Research Program will play an_essential role in fostering research into the disease. We will use DRP funding supplemented by a strong commitment of institutional funds to support innovative projects by new and established investigators, which are critical to the generation of new ideas in thyroid cancer diagnosis and treatment. Our goal is to establish mechanisms for rapid funding of important new directions to accelerate progress towards the translational research goals of our SPORE. We identified a credible portfolio of promising developmental research projects, which will be competing for support once the program is established. We will request thyroid pilot project proposals with translational potential from clinical and basic investigators within the larger MSKCC community, including Rockefeller University, New York-Presbyterian Hospital, Weill Medical College of Cornell University, as well as from the Albert Einstein College of Medicine. We will then select the most promising new projects for support after rigorous peer review by the Executive Committee, the Internal Advisory Committee and the Patient Advocates. The opinion of external reviewers will be solicited as needed. Pilot projects will be funded for 1 year, but investigators may apply for additional funding through this same competitive process the next year. Every year the Internal Advisory Committee and the Executive Committee members meet to review each research project, core and developmental pilot project. Committee members will be asked to assess whether any developmental project has progressed sufficiently and shown enough translational potential so as to eclipse that of one ofthe full research projects. The committee members will then vote and decide whether any developmental project should be advanced to full research status. If so, the budgets will be appropriately adjusted, and sent for final approval to the Physician-in-Chief and the Director of the SKI, after consultation with the TRP of the NCI.