Small molecules with large effect: The dual role of nitrogen-containing metabolites in stress tolerance and nutrient recycling

该项目的主要目标是确定干旱和营养缺乏的耐受小麦的反应途径，并提供标记育种程序，促进选择上级育种系。该项目建立在水稻中进行的一项试点研究的基础上，其中鉴定了耐受性特异性代谢物，这些代谢物代表了与保护细胞免受活性氧（ROS）损伤和压力下营养（氮，磷，糖）再循环有关的途径。现有数据表明，这些途径也与小麦有关。定量代谢组学、遗传学和分子工具将用于向育种者提供基于DNA或代谢组学的标记物。

The main objective of this project is to identify drought and nutrient-deficiency responsive pathways in tolerant wheat and to provide markers to breeding programs that facilitate selection of superior breeding lines. This project builds on a pilot study conducted in rice in which tolerant-specific metabolites were identified which are representative of pathways relevant for the protection of cells from damage through reactive oxygen species (ROS) and for nutrient (nitrogen, phosphorus, sugars) recycling under stress. Available data suggest that these pathways are also relevant in wheat. Quantitative metabolomics, genetics, and molecular tools will be used to deliver either DNA-based or metabolomics markers to breeders.