Core A: Administrative Core

抽象行政核心 管理核心(管理核心)的主要目标是作为一个中心站点，以促进 研究人员之间的沟通和互动，以支持协作，以外部科学 为确保该中心的有效治理和监督，联合国儿童基金会将继续与社区进行合作。我们的无墙中心(The 中心)将由5个不同的站点组成。该中心的研究项目具有很强的互动性。这个 互动将发生在不同的层面上，从科学(信息和数据交换、共享 资源和专门人员、初级调查人员的共同指导)到行政(组织 与国家FTD中心的会议和互动)。此外，目标、研究策略和使用 资源需要由内部执行委员会和外部顾问定期重新评估，以 在实现中心目标方面最大限度地取得进展。我们提出了四个具体目标。在目标1中，核心将 帮助总监监督中心的治理和管理，包括实施以下战略 促进各组件之间的沟通，最大限度地利用内部和外部 资源。该核心还将协调每个项目中研究人员之间的沟通， 中心与内部执行指导委员会和外部执行指导委员会之间的项目和核心 科学咨询委员会，以及中心与NINDS五个地点的管理部门之间的合作 项目工作人员，以及其他国家的FTD中心。在目标2中，核心将促进 项目和核心，并监测其实现中心所述目标的进展情况，包括与 数据核心，用于开发和维护基于网络的项目管理系统、一个公共网站和一个内联网 确保数据安全，并组织现场会议和电话会议。核心将发展和保持一个 基于Web的界面，帮助总监和指导委员会成员最大限度地提高生成和使用 中心内部和外部的资源。核心将确保中心的活动符合 联邦和机构法规，提供有关NIH法规的信息，并将及时提供报告 以及遵守临床监督和执行指导委员会的最新情况。在《目标3》中，核心 将协调外部互动，并与更广泛的研究和倡导建立关系 通过促进与Tau Consortium(TC)、Gladstone以及更广泛的 科学界。在目标4中，核心将确保及时编写进度报告和 传播研究结果和材料，包括提前通知手稿和 向NINDS项目官员提供出版物，并与NINDS通讯办公室合作出版 发布突出中心成就。

ABSTRACT — ADMINISTRATIVE CORE The main objective of the Administrative Core (Admin Core) is to serve as a central site to facilitate communication and interaction between the investigators to support collaboration, to the external scientific communities, and to ensure efficient governance and oversight of the Center. Our Center without Walls (the Center) will consist of 5 different sites. The research programs in the Center are highly interactive. The interactions will occur at different levels ranging from the scientific (exchange of information and data, sharing of resources and specialized personnel, co-mentoring of junior investigators) to the administrative (organization of meetings and interactions with national FTD centers). In addition, the goals, research strategies, and use of resources will need to be periodically reevaluated by internal executive committees and external advisors to maximize progress in achieving the aims of the Center. We propose four specific aims. In Aim 1, the Core will help the director oversee Center governance and management, including implementation of strategies to facilitate communication among the various components and maximize the use of internal and external resources. The core will also coordinate communications among the researchers in each project, between projects and the cores, between the Center and the internal Executive Steering Committee and the external Scientific Advisory Committee, and between the Center and the administration of the five sites, NINDS program staff, and the other national centers on FTD. In Aim 2, the core will promote exchanges among the projects and cores and monitor their progress toward the stated goals of the Center, including working with Data core to develop and maintain a web-based project management system, a public website and an intranet for secured data, and organize on-site meetings and teleconferences. The core will develop and maintain a web-based interface to help the director and Steering Committee members maximize the generation and use of resources, both within and external to the Center. The core will ensure that Center activities comply with federal and institutional regulations by providing information on NIH regulations and will provide timely reports and updates on compliance to the Clinical Oversight and Executive Steering Committees. In Aim 3, the core will coordinate external interactions and foster relationships with the broader research and advocacy communities by facilitating interactions with the Tau Consortium (TC), with Gladstone, and the broader scientific community. In Aim 4, the Core will ensure timely preparation of progress reports and the dissemination of research findings and materials, including providing advance notice of manuscripts and publications to the NINDS program officer and work with the NINDS Office of Communications on press releases highlighting Center accomplishments.