Administrative Core

摘要-行政核心 管理核心将作为整个桥接抗体Fc介导的抗病毒药物的资源。 在人类和非人类灵长类动物中的功能PO 1，提供全面的管理，协调和 方案的监督。P01主任格鲁吉亚托马斯将担任行政领导人， 经验丰富的核心员工将负责管理和协调整个PO 1范围 活动，监测进展情况，并确保方案的总体目标得到有效实施 而且高效。具体目标将包括以下内容。 AIM 1.提供科学监督。 AIM 2.促进整个计划的沟通。 AIM 3.确保合规性 AIM 4.提供财务监督 通过集中管理该计划的所有科学、监管和财务活动， 管理核心直接与每个项目和核心交互。同样，每个项目和 核心通过项目和核心领导的参与向行政核心提供直接投入 和主要调查人员作为该计划的执行委员会的一部分。总的来说， 杜克人类疫苗研究所在管理多机构赠款方面拥有丰富的专业知识， 将确保成功管理桥接抗体Fc介导的抗病毒功能， 人类和非人类灵长类动物P01。

ABSTRACT – Administrative Core The Administrative Core will serve as a resource to the entire Bridging Antibody Fc-mediated Antiviral Functions Across Humans and Non-human Primates PO1, providing overall management, coordination and supervision of the program. The P01 director, Georgia Tomaras will serve as the leader of the Administrative Core, and experienced staff will be responsible for managing and coordinating the entire range of the PO1 activities, monitoring progress and ensuring that the overall goals of the program are implemented effectively and efficiently. Specific Aims will include the following. AIM 1. Provide Scientific Oversight. AIM 2. Facilitate Communication across the Program. AIM 3. Ensure Regulatory Compliance AIM 4. Provide Financial Oversight Through central management of all scientific, regulatory and financial activities of the program, the Administrative Core directly interacts with each of the Projects and Cores. Similarly, each of the Projects and Cores provide direct input to the Administrative Core through the participation of the Project and Core Leads and key investigators as part of the Program’s Executive Committee. Collectively, the administrative group at the Duke Human Vaccine Institute has substantial expertise in the management of multi-institution grants and will ensure success in the management of the Bridging Antibody Fc-mediated Antiviral Functions Across Humans and Non-human Primates P01.