1/2 The North Carolina Central University (NCCU)-Duke Cancer Institute (DCI) Cancer Disparities Translational Research Partnership (NCCU-DCICDTRP)

北卡罗来纳中央大学(NCCU)-杜克大学癌症差异转化研究伙伴关系 (NCCU-DCI CDTRP)专注于开发翻译研究和培训的基础设施 非裔美国人中特定癌症致死率的增加。该计划是建立在一个长期存在的 两家总部设在达勒姆的机构之间的关系。NCCU是一家服务于服务不足的医疗机构 不平等人口和代表不足的学生(ISUPS)，附属于由17名成员组成的 北卡罗来纳州系统，杜克癌症研究所(DCI)是NCI指定的综合癌症 中心。该伙伴关系将围绕加速规划和确定优先事项展开，重点是发展 双向、互惠的癌症研究教育计划(CREP) 研究生、博士后研究员和早期研究人员的发展。规划将重点放在 建立定期讲习班、研讨会、务虚会以及更多的沟通方式和确定优先事项 将重点发展选择翻译研究和培训的前瞻性机制 首创精神。实施阶段将启动期间选定的共同开发的协作试点项目 前期计划过程，重点是前列腺癌和前列腺癌之间差异的分子翻译方面 非裔美国人的炎症性乳腺癌。NCCU和Duke之间的近25个共享资源将 可供调查人员使用。社区参与将由NCCU共同发起，它直接 服务于少数族裔社区，与DCI的卫生公平办公室和现有的差距互补 与该地区和各州未得到充分服务的少数族裔人口一起制定方案。合作伙伴关系将是 由一个由高级调查人员组成的综合行政核心(AC)领导，他们将作为初级 教师、博士后研究员和研究生，并将包括用于跟踪的外部评估计划 影响和结果。该伙伴关系将由一个内部咨询委员会(IAC)指导，该委员会是一个外部 科学咨询委员会(EAC)和社区咨询委员会(CAB)。咨询委员会的目标是： 提供NCCU-Duke CDTRP伙伴关系：1)科学和行政领导；2)行政 管理和支助；3)管理委员会和执行行政决定；4)规划 和评价；5)获得所有发展和协调中心的共享资源；6)支持职业发展和 指导调查人员；7)支持拨款申请。总而言之，咨询委员会将推动翻译 NCCU和DCI通过与这些实验室的伙伴关系进行癌症差异研究。结构化 指导任命、研讨会和年度指导委员会会议将允许领导层指导、 开展富有成效的研究活动并提供建议。AC将协助招募NCCU和杜克大学的学生 转化性癌症差异研究。此核心定义了评估进展的期望和指标 并将提供支持，允许NCCU和杜克大学的教职员工开发自给自足的研究项目。

The North Carolina Central University (NCCU) – Duke Cancer Disparities Translational Research Partnership (NCCU-DCI CDTRP) is focused on developing infrastructure for translational research and training pertaining to the increased lethality of specific cancers in African Americans. The Program is built on a long-standing relationship between two Durham-based Institutions. NCCU is an Institution Serving Underserved health disparity Populations and underrepresented Students (ISUPS), affiliated with the 17-member University of North Carolina system, and the Duke Cancer Institute (DCI) is an NCI-designated Comprehensive Cancer Center. The Partnership will develop around accelerated planning and priority-setting, focused on development of a bi-directional, mutually beneficial Cancer Research Education Program (CREP) that addresses career development for graduate students, postdoctoral fellows and early stage investigators. Planning will focus on establishing regular workshops, seminars, retreats and additional modes of communication and Priority Setting will focus on developing forward-looking mechanisms for selection of translational research and training initiatives. The Implementation stage will launch with co-developed, collaborative Pilot Projects selected during the pre-planning process, which focus on molecular translational aspects of disparities in prostate cancer and inflammatory breast cancer in African Americans. Nearly 25 Shared Resources between NCCU and Duke will be available to investigators. Community engagement will mutually co-emanate from NCCU, which directly serves a minority community, and DCI’s Office of Health Equity and Disparities with complementary existing programming with the underserved minority populations across the region and state. The Partnership will be led by an integrated Administrative Core (AC) of senior investigators who will serve as mentors to junior faculty, postdoctoral fellows and graduate students and will include an external Evaluation Program for tracking impact and outcomes. The Partnership will be guided by an Internal Advisory Committee (IAC), an External Scientific Advisory Committee (EAC) and a Community Advisory Board (CAB). The objectives of the AC are to provide for the NCCU-DUKE CDTRP Partnership: 1) Scientific and administrative leadership; 2) Administrative management and support; 3) Management of committees and implement administrative decisions; 4) Planning and Evaluation; 5) Access to all DCI and NCCU shared resources; 6) Support career development and mentorship of investigators; 7) Support for grant submissions. In summary, the AC will promote translational cancer disparities research at NCCU and DCI through partnerships with such laboratories. Structured mentoring appointments, seminars and annual steering committee meetings will allow leadership to mentor, develop and advise productive research activities. The AC will assist in recruiting NCCU and Duke students to translational cancer disparities research. This Core has defined expectations and metrics to assess progress and will provide support to allow NCCU and Duke faculty to develop self-supporting research programs.