RePORT International Consortia: Cross consortia studies elucidating the role of HIV in TB immunopathogenesis and biomarker discovery across Brazil, India and South Africa

国家过敏和传染病研究所（NIAID）、艾滋病司（DAIDS）；在国家卫生和科学部的国内代表和支持下，共同建立了结核病区域前瞻性观察研究（报告），以全面了解结核病/艾滋病毒合并感染人群中结核病的发病机制。结核病仍然是全世界感染相关死亡的主要原因，报告所述国家承担的这一负担比例最大。《国际报告》的目的是促进在全球范围内也具有相关性的区域结核病科学；在结核病高负担地区加强结核病研究能力和基础设施；并作为一个实体，促进各国国内和国际上的研究合作，目的是开展广泛的基础和临床研究，从而产生具有临床重要性的结核病生物标志物、疫苗、药物和诊断方法。

The National Institute of Allergy and Infectious Diseases (NIAID), Division of AIDS (DAIDS); together with in-country representation and support from National Health and Science ministries have jointly established the Regional Prospective Observational Research in Tuberculosis (RePORT) to gain a comprehensive understanding of the pathogenesis of TB in TB/HIV co-infected populations. TB remains a leading cause of infection-related death worldwide with the countries represented under RePORT carrying the largest proportion of this burden. The purpose of RePORT International is to advance regional tuberculosis (TB) science that is also relevant in a global context; strengthen TB research capacity and infrastructure in high TB burden settings; and serve as an entity to foster research collaboration within each country and internationally, with the aim of carrying out a wide range of basic and clinical research that can lead to clinically important TB biomarkers, vaccines, drugs, and diagnostics.